PCGF1 Antikörper (AA 51-150) (Biotin)

Produktnummer ABIN1397136

Produktdetails anti-PCGF1 Antikörper (Biotin)

Target: PCGF1 (Polycomb Group Ring Finger 1 (PCGF1))

Bindungsspezifität: AA 51-150

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCGF1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PCGF1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu PCGF1

Target: PCGF1 (Polycomb Group Ring Finger 1 (PCGF1))

Andere Bezeichnung: PCGF1 (PCGF1 Produkte)

Synonyme: PCGF1 antikoerper, 2010002K04Rik antikoerper, NSPC1 antikoerper, RNF3A-2 antikoerper, RNF68 antikoerper, AU024121 antikoerper, Nspc1 antikoerper, nspc1 antikoerper, si:zc207o21.2 antikoerper, polycomb group ring finger 1 antikoerper, polycomb group ring finger 1 L homeolog antikoerper, PCGF1 antikoerper, pcgf1 antikoerper, Pcgf1 antikoerper, pcgf1.L antikoerper

Hintergrund:

Synonyms: PCGF1_HUMAN, PCGF1, Nervous system Polycomb-1, NSPc1, Polycomb group RING finger protein 1, RING finger protein 68, RNF68.

Background: PCGF1 is a component of the Polycomb group (PcG) multiprotein BCOR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as BCL6 and the cyclin-dependent kinase inhibitor, CDKN1A. It represses CDKN1A expression by binding to its promoter, and this repression is dependent on the retinoic acid response element (RARE element). PCGF1 als promotes cell cycle progression and also enhances cell proliferation, thus it may have a positive role in tumor cell growth.