Chromosome 5 Open Reading Frame 39 (C5orf39) (AA 50-100) Antikörper (AbBy Fluor® 350)
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- Target Alle Chromosome 5 Open Reading Frame 39 (C5orf39) Antikörper anzeigen
- Chromosome 5 Open Reading Frame 39 (C5orf39)
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Bindungsspezifität
- AA 50-100
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- AbBy Fluor® 350
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Applikation
- Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Homologie
- Human
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Annexin-2 receptor
- Isotyp
- IgG
- Top Product
- Discover our top product C5orf39 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Chromosome 5 Open Reading Frame 39 (C5orf39)
- Andere Bezeichnung
- AX2R (C5orf39 Produkte)
- Synonyme
- AX2R antikoerper, AXIIR antikoerper, C5orf39 antikoerper, annexin A2 receptor antikoerper, ANXA2R antikoerper
- Hintergrund
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Synonyms: LOC389289, ANXA2R, Annexin 2 receptor, Annexin II receptor, AX2R, AXIIR, C5orf39, Chromosome 5 open reading frame 39, AX2R_HUMAN.
Background: ANXA2R (annexin-2 receptor), also known as AX2R or C5orf39, is a 193 amino acid protein that is widely expressed and may act as an annexin II receptor on marrow stromal cells to induce osteoclast formation. In addition, ANXA2R is highly expressed in lymphocytes and is also found in resting CD4+ and CD8+ T cells. The gene encoding ANXA2R maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6 % of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
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