DIRC2 Antikörper (AA 51-150) (Biotin)

Produktnummer ABIN1398169

Produktdetails anti-DIRC2 Antikörper (Biotin)

Target: DIRC2 (Disrupted in Renal Carcinoma 2 (DIRC2))

Bindungsspezifität: AA 51-150

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DIRC2 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DIRC2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu DIRC2

Target: DIRC2 (Disrupted in Renal Carcinoma 2 (DIRC2))

Andere Bezeichnung: DIRC2 (DIRC2 Produkte)

Synonyme: MGC80843 antikoerper, zgc:92095 antikoerper, rcc4 antikoerper, MGC69320 antikoerper, RCC4 antikoerper, disrupted in renal carcinoma 2 antikoerper, disrupted in renal carcinoma 2 L homeolog antikoerper, disrupted in renal carcinoma 2 (human) antikoerper, DIRC2 antikoerper, dirc2.L antikoerper, dirc2 antikoerper, Dirc2 antikoerper

Hintergrund:

Synonyms: Disrupted in renal carcinoma protein 2, DIRC 2, Disrupted in renal cancer protein 2, Disrupted in renal carcinoma 2, FLJ14784, NP_116228, RCC 4, RCC4, Renal cell carcinoma 4, DIRC2_HUMAN.

Background: Belonging to the major facilitator superfamily, DIRC2 (disrupted in renal carcinoma protein 2) is a 478 amino acid multi-pass membrane protein that is primarily expressed in kidney proximal tubular cells. The genes encoding DIRC2 and DIRC3 are located at a translocation breakpoint which occurs frequently in individuals affected by familial renal cell carcinoma. Fusion transcripts that result from these translocations may affect normal protein function. This evidence suggests that, due to its chromosomal location, deregulation of the DIRC2 gene may cause haploinsufficiency and therefore result in the onset of tumor growth. There are two isoforms of DIRC2 which are produced as a result of alternative splicing events.

Gen-ID: 84925