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OSTM1 Antikörper (AA 21-120) (FITC)

OSTM1 Reaktivität: Human, Ratte, Maus WB, FACS, IF (p), IF (cc) Wirt: Kaninchen Polyclonal FITC
Produktnummer ABIN1399442
  • Target Alle OSTM1 Antikörper anzeigen
    OSTM1 (Osteopetrosis Associated Transmembrane Protein 1 (OSTM1))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    Reaktivität
    • 37
    • 19
    • 19
    • 3
    Human, Ratte, Maus
    Wirt
    • 37
    • 1
    Kaninchen
    Klonalität
    • 37
    • 1
    Polyklonal
    Konjugat
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser OSTM1 Antikörper ist konjugiert mit FITC
    Applikation
    • 38
    • 17
    • 16
    • 12
    • 12
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human OSTM1
    Isotyp
    IgG
    Top Product
    Discover our top product OSTM1 Primärantikörper
  • Applikationshinweise
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    OSTM1 (Osteopetrosis Associated Transmembrane Protein 1 (OSTM1))
    Andere Bezeichnung
    OSTM1 (OSTM1 Produkte)
    Synonyme
    MGC145644 antikoerper, si:ch73-257c13.3 antikoerper, GIPN antikoerper, GL antikoerper, OPTB5 antikoerper, 1200002H13Rik antikoerper, HSPC019 antikoerper, gl antikoerper, Gipn antikoerper, OSTM1 antikoerper, osteopetrosis associated transmembrane protein 1 antikoerper, OSTM1 antikoerper, ostm1 antikoerper, Ostm1 antikoerper
    Hintergrund

    Synonyms: GL, GIPN, OPTB5, HSPC019, Osteopetrosis-associated transmembrane protein 1, Chloride channel 7 beta subunit, OSTM1, UNQ6098/PRO21201

    Background: OSTM1 (osteopetrosis associated transmembrane protein 1), also known as gl (gray-lethal) or HSPC019, is a 338 amino acid single-pass type I membrane protein that is expressed primarily in osteoclasts and melanocytes as well as brain, kidney and spleen. Bone autosomal recessive osteopetrosis (ARO) is the most severe form of hereditary bone disease whose cellular basis is in the osteoclast and is characterized by abnormally dense bone, due to defective resorption of immature bone. ARO is suggested to be caused by mutations in the OSTM1 gene. The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or adulthood. Defects in the OSTM1 gene are also the cause of the spontaneous gl mutant, which is responsible for a coat color defect in mice.

    Gen-ID
    28962
    UniProt
    Q86WC4
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