OSTM1 Antikörper (AA 21-120) (FITC)
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- Target Alle OSTM1 Antikörper anzeigen
- OSTM1 (Osteopetrosis Associated Transmembrane Protein 1 (OSTM1))
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Bindungsspezifität
- AA 21-120
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser OSTM1 Antikörper ist konjugiert mit FITC
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Kreuzreaktivität
- Human, Maus, Ratte
- Homologie
- Pig
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human OSTM1
- Isotyp
- IgG
- Top Product
- Discover our top product OSTM1 Primärantikörper
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- Applikationshinweise
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- OSTM1 (Osteopetrosis Associated Transmembrane Protein 1 (OSTM1))
- Andere Bezeichnung
- OSTM1 (OSTM1 Produkte)
- Synonyme
- MGC145644 antikoerper, si:ch73-257c13.3 antikoerper, GIPN antikoerper, GL antikoerper, OPTB5 antikoerper, 1200002H13Rik antikoerper, HSPC019 antikoerper, gl antikoerper, Gipn antikoerper, OSTM1 antikoerper, osteopetrosis associated transmembrane protein 1 antikoerper, OSTM1 antikoerper, ostm1 antikoerper, Ostm1 antikoerper
- Hintergrund
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Synonyms: GL, GIPN, OPTB5, HSPC019, Osteopetrosis-associated transmembrane protein 1, Chloride channel 7 beta subunit, OSTM1, UNQ6098/PRO21201
Background: OSTM1 (osteopetrosis associated transmembrane protein 1), also known as gl (gray-lethal) or HSPC019, is a 338 amino acid single-pass type I membrane protein that is expressed primarily in osteoclasts and melanocytes as well as brain, kidney and spleen. Bone autosomal recessive osteopetrosis (ARO) is the most severe form of hereditary bone disease whose cellular basis is in the osteoclast and is characterized by abnormally dense bone, due to defective resorption of immature bone. ARO is suggested to be caused by mutations in the OSTM1 gene. The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or adulthood. Defects in the OSTM1 gene are also the cause of the spontaneous gl mutant, which is responsible for a coat color defect in mice.
- Gen-ID
- 28962
- UniProt
- Q86WC4
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