CLEC4E Antikörper (AA 51-150) (AbBy Fluor® 555)
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- Target Alle CLEC4E Antikörper anzeigen
- CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))
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Bindungsspezifität
- AA 51-150
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Reaktivität
- Human, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CLEC4E Antikörper ist konjugiert mit AbBy Fluor® 555
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Ratte
- Homologie
- Mouse,Cow,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CLECSF9/CLEC4E
- Isotyp
- IgG
- Top Product
- Discover our top product CLEC4E Primärantikörper
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- Applikationshinweise
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))
- Andere Bezeichnung
- CLEC 4E (CLEC4E Produkte)
- Synonyme
- CLECSF9 antikoerper, MINCLE antikoerper, C86253 antikoerper, Clecsf9 antikoerper, Mincle antikoerper, CLEC4E antikoerper, C-type lectin domain family 4 member E antikoerper, C-type lectin domain family 4, member e antikoerper, C-type lectin domain family 4, member E antikoerper, CLEC4E antikoerper, Clec4e antikoerper, LOC611538 antikoerper
- Hintergrund
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Synonyms: C type lectin domain family 4 member E, C type lectin superfamily member 9, C-type calcium dependent carbohydrate recognition domain lectin superfamily member 9, C-type lectin domain family 4 member E, C-type lectin superfamily member 9, CLC4E_HUMAN, CLEC 4E, CLEC4E Clec4e, CLECSF9, Macrophage inducible C type lectin, Macrophage-inducible C-type lectin, MINCLE.
Background: C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.
- Gen-ID
- 26253
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