MLLT11 Antikörper (AA 41-90) (AbBy Fluor® 647)
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- Target Alle MLLT11 Antikörper anzeigen
- MLLT11 (Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog), Translocated To, 11 (MLLT11))
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Bindungsspezifität
- AA 41-90
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MLLT11 Antikörper ist konjugiert mit AbBy Fluor® 647
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Applikation
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human
- Homologie
- Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human MLLT11
- Isotyp
- IgG
- Top Product
- Discover our top product MLLT11 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- MLLT11 (Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog), Translocated To, 11 (MLLT11))
- Andere Bezeichnung
- MLLT11 (MLLT11 Produkte)
- Synonyme
- AF1Q antikoerper, RP11-316M1.10 antikoerper, AI839562 antikoerper, Af1q antikoerper, Zfp692 antikoerper, RGD1305525 antikoerper, fc23g02 antikoerper, si:ch211-210h11.4 antikoerper, wu:fc23g02 antikoerper, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 antikoerper, MLLT11, transcription factor 7 cofactor antikoerper, MLLT11 antikoerper, Mllt11 antikoerper, mllt11 antikoerper
- Hintergrund
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Synonyms: AF1Q, ALL1 fused gene from chromosome 1q, MLLT 11, MLLT-11, Myeloid/lymphoid or mixed lineage leukemia trithorax homolog, Drosophila translocated to 11, Protein AF1q, RP11 316M1.10.
Background: The gene encoding the Mixed-Lineage Leukemia (MLL) proteins is located on chromosome 11q23. Chromosomal translocations involving band 11q23 result in rogue activator proteins that are associated with approximately 10 % of patients with acute lymphoblastic leukemia (ALL) and 5 % of patients with acute myeloid leukemia (AML). Most patients affected are less than 1 year of age. MLLT11, also known as mixed-lineage leukemia translocated to 11 or AF1q, is a 90 amino acid MLL fusion partner. Based on the expression patterns of MLLT11, it is thought that MLLT11 plays a role in leukemogenesis and, specifically, the progression of acute monocytic leukemia (AML). Also, expressed in embryonic brain cortex, MLLT11 is upregulated during neuronal differentiation and is thought to play a role in the development of the central nervous system. Finally, MLLT11 has been shown to be differentially expressed in highly metastatic cells, in comparison with non-metastatic parent cells. Such findings suggest a role of MLLT11 in tumorigenesis.
- Gen-ID
- 10962
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