C9ORF72 Antikörper (AA 391-481) (Biotin)

Produktnummer ABIN1399939

Produktdetails anti-C9ORF72 Antikörper (Biotin)

Target: C9ORF72 (Chromosome 9 Open Reading Frame 72 (C9ORF72))

Bindungsspezifität: AA 391-481

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C9ORF72 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C9orf72

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu C9ORF72

Target: C9ORF72 (Chromosome 9 Open Reading Frame 72 (C9ORF72))

Andere Bezeichnung: C9orf72 (C9ORF72 Produkte)

Synonyme: CZH9orf72 antikoerper, ALSFTD antikoerper, FTDALS antikoerper, AI840585 antikoerper, c9orf72 antikoerper, chromosome Z C9orf72 homolog antikoerper, chromosome 9 open reading frame 72 antikoerper, RIKEN cDNA 3110043O21 gene antikoerper, similar to RIKEN cDNA 3110043O21 antikoerper, chromosome 9 open reading frame 72 L homeolog antikoerper, CZH9orf72 antikoerper, C9orf72 antikoerper, 3110043O21Rik antikoerper, RGD1359108 antikoerper, c9orf72.L antikoerper

Hintergrund:

Synonyms: ALSFTD, FTDALS, Protein C9orf72, C9orf72

Background: Chromosome 9 consists of about 145 million bases and 4 % of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The C9orf72 gene product has been provisionally designated C9orf72 pending further characterization. There are two isoforms of C9orf72 that are produced as a result of alternative splicing events.

Gen-ID: 203228

UniProt: Q96LT7