MMS19 Antikörper (AA 851-950) (AbBy Fluor® 647)
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- Target Alle MMS19 Antikörper anzeigen
- MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))
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Bindungsspezifität
- AA 851-950
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MMS19 Antikörper ist konjugiert mit AbBy Fluor® 647
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus
- Homologie
- Rat,Dog,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human MMS 19
- Isotyp
- IgG
- Top Product
- Discover our top product MMS19 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))
- Andere Bezeichnung
- MMS19 (MMS19 Produkte)
- Synonyme
- MET18 antikoerper, MMS19L antikoerper, hMMS19 antikoerper, 2410001K24Rik antikoerper, 2610042O15Rik antikoerper, AI316855 antikoerper, C79368 antikoerper, C86341 antikoerper, Mms19l antikoerper, mms19 antikoerper, mms19l antikoerper, MMS19 homolog, cytosolic iron-sulfur assembly component antikoerper, MMS19 (MET18 S. cerevisiae) antikoerper, MMS19 homolog, cytosolic iron-sulfur assembly component L homeolog antikoerper, MMS19 antikoerper, Mms19 antikoerper, mms19.L antikoerper
- Hintergrund
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Synonyms: MET18, MMS19L, hMMS19, MMS19 nucleotide excision repair protein homolog, MET18 homolog, MMS19-like protein, MMS19
Background: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.
- Gen-ID
- 64210
- UniProt
- Q96T76
- Pathways
- Nuclear Hormone Receptor Binding
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