ERN1 Antikörper (AA 252-260) (FITC)
(1 reference)-
- Target Alle ERN1 Antikörper anzeigen
- ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))
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Bindungsspezifität
- AA 252-260
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Reaktivität
- Human, Maus, Ratte, Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ERN1 Antikörper ist konjugiert mit FITC
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus, Schwein, Ratte
- Homologie
- Dog,Cow,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human IRE1a
- Isotyp
- IgG
- Top Product
- Discover our top product ERN1 Primärantikörper
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anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 401-500) antibody
ERN1 Reaktivität: Human WB, ELISA, IF, PLA Wirt: Maus Monoclonal 8D12 unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 282-433) antibodyERN1 Reaktivität: Human WB, ELISA, IHC Wirt: Maus Monoclonal 9F2 unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 401-500) antibodyERN1 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 3D1 unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (pSer726) antibodyERN1 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IF (cc), IF (p), ICC, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 252-260) antibodyERN1 Reaktivität: Human, Maus, Ratte, Schwein WB, ELISA, FACS, IF (cc), IF (p), ICC, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (pSer724) antibodyERN1 Reaktivität: Human WB, ELISA, IF Wirt: Kaninchen Monoclonal 1F12 unconjugated Recombinant Antibody
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (Internal Region) antibodyVerified ERN1 Reaktivität: Human WB, ELISA, FACS Wirt: Ziege Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (C-Term) antibodyERN1 Reaktivität: Human, Maus, Ratte WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 493-561) antibodyERN1 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 828-857), (C-Term) antibodyERN1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB16565 unconjugated
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- Applikationshinweise
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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: "IRE1?-XBP1 Pathway Is Activated Upon Induction of Single-Prolonged Stress in Rat Neurons of the Medial Prefrontal Cortex." in: Journal of molecular neuroscience : MN, (2015) (PubMed).
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: "IRE1?-XBP1 Pathway Is Activated Upon Induction of Single-Prolonged Stress in Rat Neurons of the Medial Prefrontal Cortex." in: Journal of molecular neuroscience : MN, (2015) (PubMed).
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- Target
- ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))
- Andere Bezeichnung
- IRE1a (ERN1 Produkte)
- Hintergrund
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Synonyms: IRE1, IRE1P, IRE1a, hIRE1p, Serine/threonine-protein kinase/endoribonuclease IRE1, Endoplasmic reticulum-to-nucleus signaling 1, Inositol-requiring protein 1, Ire1-alpha, ERN1
Background: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
- Gen-ID
- 2081
- UniProt
- O75460
- Pathways
- ER-Nucleus Signaling, Unfolded Protein Response
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