BRMS1 Antikörper (AA 151-246) (AbBy Fluor® 350)
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- Target Alle BRMS1 Antikörper anzeigen
- BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
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Bindungsspezifität
- AA 151-246
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser BRMS1 Antikörper ist konjugiert mit AbBy Fluor® 350
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Homologie
- Dog,Pig,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human BRMS1
- Isotyp
- IgG
- Top Product
- Discover our top product BRMS1 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
- Andere Bezeichnung
- BRMS1 (BRMS1 Produkte)
- Synonyme
- MGC98869 antikoerper, BRMS1 antikoerper, BRMS1L antikoerper, AV003220 antikoerper, AW554636 antikoerper, si:zc188c22.3 antikoerper, si:zc194c5.2 antikoerper, wu:fb57b08 antikoerper, zgc:56414 antikoerper, breast cancer metastasis suppressor 1 antikoerper, breast cancer metastasis-suppressor 1 antikoerper, breast cancer metastasis suppressor 1 L homeolog antikoerper, BRMS1 antikoerper, Brms1 antikoerper, brms1.L antikoerper, brms1 antikoerper
- Hintergrund
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Synonyms: Breast cancer metastasis suppressor 1, Breast cancer metastasis-suppressor 1, BRMS-1, BRMS1_HUMAN, DKFZp564A063, MGC95128, AV003220, AW554636.
Background: Breast cancer metastasis-suppressor 1 (BRMS1) is 246 amino acid protein that acts as a mediator of metastasis suppression in several types of cancer including ovarian, lung, bladder, and murine mammary. BRMS1 mRNA is expressed in various tissues, including ovary, prostate, testis, and colon, but the protein is primarily detected in term placenta. BRMS1 suppresses metastasis without inhibiting tumorigenicity by modifying several metastasis-associated phenotypes. BRMS1 may participate in transcriptional regulation by binding to the mSin3/histone deacetylase complex. The expression of BRMS1 in certain cells increases connexin Cx43 expression and reduces connexin Cx32 expression. This produces a gap junction that increases intercellular communication, similar to those found in normal breast tissue. BRMS1 is stabilized by Hsp90 and may inhibit NF-_B activity.
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