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MEPE Antikörper (AA 201-300) (Biotin)

MEPE Reaktivität: Maus WB, ELISA, IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1400191
  • Target Alle MEPE Antikörper anzeigen
    MEPE (Matrix Extracellular phosphoglycoprotein (MEPE))
    Bindungsspezifität
    • 14
    • 8
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300
    Reaktivität
    • 22
    • 17
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 36
    • 2
    • 1
    Kaninchen
    Klonalität
    • 37
    • 2
    Polyklonal
    Konjugat
    • 17
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MEPE Antikörper ist konjugiert mit Biotin
    Applikation
    • 38
    • 18
    • 13
    • 13
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Maus
    Homologie
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MEPE
    Isotyp
    IgG
    Top Product
    Discover our top product MEPE Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    MEPE (Matrix Extracellular phosphoglycoprotein (MEPE))
    Andere Bezeichnung
    MEPE (MEPE Produkte)
    Synonyme
    OF45 antikoerper, OC-116 antikoerper, Of45 antikoerper, matrix extracellular phosphoglycoprotein antikoerper, matrix extracellular phosphoglycoprotein with ASARM motif (bone) antikoerper, MEPE antikoerper, Mepe antikoerper, LOC789774 antikoerper
    Hintergrund

    Synonyms: Matrix extracellular phosphoglycoprotein, MEPE, MEPE_HUMAN, OF45, Osteoblast/osteocyte factor 45.

    Background: MEPE is a 525 amino acid extracellular matrix protein. Expressed in osteocytes and brain, MEPE is a regulator of bone metabolism that is thought to mediate mineralization and demineralization within the osteocyte microenvironment. MEPE contains an RGD cell-attachment motif and shares molecular similarities with several dentin-bone extracellular matrix RGD-containing phosphoglycoproteins, including OPN (osteopontin) and DSP (dentin sialophosphoprotein). Via its ability to control bone mineralization, MEPE is associated with various developmental events such as skeletogenesis, bone regeneration and odontogenesis. MEPE is secreted in hypophosphatemic osteomalacia tumors, suggesting a possible role in the pathophysiology of bone-related cancers.

    Gen-ID
    56955
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