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RSAD2 Antikörper (Biotin)

RSAD2 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1400227
  • Target Alle RSAD2 Antikörper anzeigen
    RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))
    Reaktivität
    • 43
    • 28
    • 21
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 39
    • 5
    • 1
    Kaninchen
    Klonalität
    • 40
    • 5
    Polyklonal
    Konjugat
    • 26
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RSAD2 Antikörper ist konjugiert mit Biotin
    Applikation
    • 38
    • 13
    • 9
    • 8
    • 7
    • 4
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Viperin/RSAD2
    Isotyp
    IgG
    Top Product
    Discover our top product RSAD2 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))
    Andere Bezeichnung
    Viperin (RSAD2 Produkte)
    Synonyme
    CIG6 antikoerper, RSAD2 antikoerper, 2510004L01Rik antikoerper, cig33 antikoerper, cig5 antikoerper, vig1 antikoerper, Vig1 antikoerper, Best5 antikoerper, si:ch211-276e8.2 antikoerper, zgc:112342 antikoerper, viperin antikoerper, rsad2 antikoerper, radical S-adenosyl methionine domain containing 2 antikoerper, viperin antikoerper, RSAD2 antikoerper, Rsad2 antikoerper, rsad2 antikoerper, vig1 antikoerper
    Hintergrund

    Synonyms: endoplasmic reticulum-associated, interferon-inducible, cig 33, CIG 5, cig-33, CIG-5, CIG33, CIG5, Cytomegalovirus induced gene 5 protein, Cytomegalovirus-induced gene 5 protein, Radical S-adenosyl methionine domain-containing protein 2, RSAD 2, Rsad2, RSAD2_HUMAN, RSDA-2, VIG 1, vig1, Viperin, Virus inhibitory protein, virus inhibitory protein endoplasmic reticulum associated interferon inducible.

    Background: RSAD2 is a 361 amino acid protein that is involved in antiviral defense against pathogens such as Hep C, Cytomegalovirus and HIV-1. Localized to the cytosolic side of the endoplasmic reticulum and relocated to the Golgi apparatus upon viral infection, RSAD2 is thought to prevent viral budding by disrupting lipid rafts at the plasma membrane and supporting the Interferon-induced antiviral state of the cell. Additionally, RSAD2 can bind to and inactivate FDPS (an enzyme that is crucial for the synthesis of cholesterol and geranylated and farnesylated proteins), thereby playing a role in lipid synthesis. Overexpression of RSAD2 leads to abnormal lipid accumulation that is associated with atherosclerosis, a chronic inflammatory disease characterized by hardened arteries.

    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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