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SARM1 Antikörper (AA 340-380) (FITC)

SARM1 Reaktivität: Human, Maus, Ratte WB, IF (p) Wirt: Kaninchen Polyclonal FITC
Produktnummer ABIN1400264
  • Target Alle SARM1 Antikörper anzeigen
    SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))
    Bindungsspezifität
    • 14
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 340-380
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 22
    • 3
    Kaninchen
    Klonalität
    • 22
    • 3
    Polyklonal
    Konjugat
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SARM1 Antikörper ist konjugiert mit FITC
    Applikation
    • 22
    • 12
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SARM1
    Isotyp
    IgG
    Top Product
    Discover our top product SARM1 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))
    Andere Bezeichnung
    SARM1 (SARM1 Produkte)
    Synonyme
    A830091I15Rik antikoerper, C78606 antikoerper, MyD885 antikoerper, Sarm antikoerper, MyD88-5 antikoerper, SAMD2 antikoerper, SARM antikoerper, sterile alpha and TIR motif containing 1 antikoerper, sterile alpha and HEAT/Armadillo motif containing 1 antikoerper, SARM1 antikoerper, Sarm1 antikoerper, sarm1 antikoerper
    Hintergrund

    Synonyms: SARM, SAMD2, MyD88-5, Sterile alpha and TIR motif-containing protein 1, Sterile alpha and Armadillo repeat protein, Sterile alpha motif domain-containing protein 2, SAM domain-containing protein 2, Tir-1 homolog, SARM1, KIAA0524

    Background: Negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway which plays a pivotal role in activating axonal degeneration following injury. Promotes Wallerian degeneration an injury-induced axonal death pathway which involves degeneration of an axon distal to the injury site. Can activate neuronal death in response to stress. Regulates dendritic arborization through the MAPK4-JNK pathway. Involved in innate immune response. Inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1, TRIF-dependent activation of NF-kappa-B and IRF3, and the phosphorylation of MAPK14/p38.

    Gen-ID
    23098
    UniProt
    Q6SZW1
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades
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