TENM3 Antikörper (AbBy Fluor® 647)

Produktnummer ABIN1400610

Produktdetails anti-TENM3 Antikörper (AbBy Fluor® 647)

Target: TENM3 (ODZ3) (Teneurin 3 (ODZ3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TENM3 Antikörper ist konjugiert mit AbBy Fluor® 647

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ODZ3/Teneurin 3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TENM3

Target: TENM3 (ODZ3) (Teneurin 3 (ODZ3))

Andere Bezeichnung: ODZ3 (ODZ3 Produkte)

Synonyme: MCOPCB9 antikoerper, ODZ3 antikoerper, TNM3 antikoerper, Ten-m3 antikoerper, cb399 antikoerper, id:ibd3379m antikoerper, odz3 antikoerper, srs334 antikoerper, ten-3 antikoerper, ten-m3 antikoerper, Odz3 antikoerper, ODZ1 antikoerper, DKFZp459E2420 antikoerper, 2610100B16Rik antikoerper, Odz1 antikoerper, mKIAA1455 antikoerper, teneurin-3 antikoerper, teneurin transmembrane protein 3 antikoerper, teneurin-3 antikoerper, TENM3 antikoerper, tenm3 antikoerper, Tenm3 antikoerper, LOC100083546 antikoerper, LOC100174129 antikoerper, LOC100457434 antikoerper

Hintergrund:

Synonyms: ODZ3 like protein, Protein Odd Oz ten m homolog 3, Ten 3, Ten M3, Tenascin M3, Teneurin 3, Teneurin3, TNM3, FLJ10474, FLJ10886, KIAA1455, odd Oz Ten m homolog 3, odz odd Oz ten m homolog 3 Drosophila, odz odd Oz ten m homolog 3, TEN3_HUMAN.

Background: Teneurin-3, also known as Ten-3, TNM3 or ODZ3, is a 2,699 amino acid single-pass type II membrane protein that contains 25 YD repeats, 8 EGF-like domains, 5 NHL repeats and one teneurin N-terminal domain. Localized to the membrane and expressed in brain, testis and ovary, Teneurin-3 exists as a disulfide-liked homodimer that is thought to function as a cellular signal transducer. Additionally, Teneurin-3 may participate in eye-specific patterning in the visual pathway and is required for aligned binocular vision. The gene encoding Teneurin-3 maps to chromosome 4. Representing approximately 6 % of the human genome, chromosome 4 contains nearly 900 genes, one of which is the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.