COPS4 Antikörper (AbBy Fluor® 488)
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- Target Alle COPS4 Antikörper anzeigen
- COPS4 (COP9 Signalosome Subunit 4 (COPS4))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser COPS4 Antikörper ist konjugiert mit AbBy Fluor® 488
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Applikation
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human COPS4
- Isotyp
- IgG
- Top Product
- Discover our top product COPS4 Primärantikörper
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anti-COP9 Signalosome Subunit 4 (COPS4) (AA 1-310) antibody
COPS4 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Signalosome Subunit 4 (COPS4) (AA 53-102) antibodyCOPS4 Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Meerschweinchen, Schwein, Fledermaus, Hamster, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Signalosome Subunit 4 (COPS4) (AA 143-192) antibodyCOPS4 Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Meerschweinchen, Schwein, Zebrafisch (Danio rerio), Huhn, Fledermaus, Hamster, Affe, Xenopus laevis WB Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Signalosome Subunit 4 (COPS4) (Middle Region) antibodyCOPS4 Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Meerschweinchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- IF(IHC-P) 1:50-200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- COPS4 (COP9 Signalosome Subunit 4 (COPS4))
- Andere Bezeichnung
- COPS4 (COPS4 Produkte)
- Hintergrund
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Synonyms: CH4, COP9 constitutive photomorphogenic homolog subunit 4, COP9 complex homolog subunit 4, COP9 complex S4, COP9 constitutive photomorphogenic homolog subunit 4, COP9 signalosome complex subunit 4, COP9 signalosome subunit 4, COPS4, CSN complex subunit 4, CSN4, CSN4 SCHPO, CSN4_HUMAN, DCH4, JAB1 containing signalosome subunit 4, JAB1-containing signalosome subunit 4, MGC94896, SGN4, Signalosome subunit 4.
Background: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
- Gen-ID
- 51138
- Pathways
- Zellzyklus
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