COPS7A Antikörper (AbBy Fluor® 647)
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- Target Alle COPS7A Antikörper anzeigen
- COPS7A (COP9 Signalosome Complex Subunit 7a (COPS7A))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser COPS7A Antikörper ist konjugiert mit AbBy Fluor® 647
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human COPS7A
- Isotyp
- IgG
- Top Product
- Discover our top product COPS7A Primärantikörper
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- Applikationshinweise
- IF(IHC-P) 1:50-200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- COPS7A (COP9 Signalosome Complex Subunit 7a (COPS7A))
- Andere Bezeichnung
- COPS7A (COPS7A Produkte)
- Synonyme
- D6Ertd35e antikoerper, CSN7A antikoerper, COP9 signalosome subunit 7A antikoerper, COPS7A antikoerper, Cops7a antikoerper
- Hintergrund
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Synonyms: COP9 signalosome complex subunit 7a, SGN7a, Signalosome subunit 7a, Dermal papilla-derived protein 10, JAB1-containing signalosome subunit 7a, COPS7A, CSN7A, DERP10, CSN7A_HUMAN.
Background: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
- Gen-ID
- 50813
- UniProt
- Q9UBW8
- Pathways
- Zellzyklus
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