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SH3RF1 Antikörper (AbBy Fluor® 488)

SH3RF1 Reaktivität: Human, Maus, Ratte WB, IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 488
Produktnummer ABIN1401154
  • Target Alle SH3RF1 Antikörper anzeigen
    SH3RF1 (SH3 Domain Containing Ring Finger 1 (SH3RF1))
    Reaktivität
    • 26
    • 18
    • 17
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 23
    • 3
    Kaninchen
    Klonalität
    • 24
    • 2
    Polyklonal
    Konjugat
    • 10
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SH3RF1 Antikörper ist konjugiert mit AbBy Fluor® 488
    Applikation
    • 22
    • 12
    • 7
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SH3MD2/RNF142
    Isotyp
    IgG
    Top Product
    Discover our top product SH3RF1 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    SH3RF1 (SH3 Domain Containing Ring Finger 1 (SH3RF1))
    Andere Bezeichnung
    RNF142 (SH3RF1 Produkte)
    Synonyme
    SH3MD2 antikoerper, posh antikoerper, xPOSH antikoerper, rnf142 antikoerper, sh3md2 antikoerper, MGC135632 antikoerper, MGC189605 antikoerper, POSH antikoerper, RNF142 antikoerper, 2200003J05Rik antikoerper, Posh antikoerper, R75531 antikoerper, Sh3md2 antikoerper, si:ch211-114c9.2 antikoerper, si:dkey-15j16.4 antikoerper, wu:fi42f11 antikoerper, SH3 domain containing ring finger 1 antikoerper, SH3 domain containing ring finger 1 S homeolog antikoerper, SH3RF1 antikoerper, sh3rf1 antikoerper, sh3rf1.S antikoerper, Sh3rf1 antikoerper
    Hintergrund

    Synonyms: Plenty of SH3 domains, Plenty of SH3s, POSH, Ring finger protein 142, RNF 142, RNF142, SH3 domain containing ring finger 1, SH3 domain containing RING finger protein 1, SH3MD2, SH3 multiple domains 2, SH3RF1.

    Background: SH3MD2 acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9). SH3MD2 may be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane. This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module. There are two named isoforms.

    Gen-ID
    57630
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