TRIM39 Antikörper (Biotin)

Produktnummer ABIN1401649

Produktdetails anti-TRIM39 Antikörper (Biotin)

Target: TRIM39 (Tripartite Motif Containing 39 (TRIM39))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM39 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RNF23

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu TRIM39

Target: TRIM39 (Tripartite Motif Containing 39 (TRIM39))

Andere Bezeichnung: RNF23 (TRIM39 Produkte)

Synonyme: TRIM39.2 antikoerper, MGC78802 antikoerper, TRIM39 antikoerper, DKFZp459K1530 antikoerper, RNF23 antikoerper, TFP antikoerper, TRIM39B antikoerper, RPP21 antikoerper, 1100001D15Rik antikoerper, E130103K13Rik antikoerper, RBCC-B30.2 antikoerper, Rnf23 antikoerper, mKIAA4179 antikoerper, tfp antikoerper, tripartite motif containing 39.2 antikoerper, tripartite motif containing 39 L homeolog antikoerper, E3 ubiquitin-protein ligase TRIM39 antikoerper, tripartite motif containing 39 antikoerper, tripartite motif-containing 39 antikoerper, TRIM39.2 antikoerper, trim39.L antikoerper, LOC100022234 antikoerper, trim39 antikoerper, TRIM39 antikoerper, LOC615278 antikoerper, Trim39 antikoerper

Hintergrund:

Synonyms: Ring finger protein 23, RNF23, Testis abundant finger protein, TFP, TFP RING FINGER PROTEIN 23, TRIM39, Tripartite mot containing 39, TRI39_HUMAN.

Background: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF23 (RING finger protein 23), also known as tripartite motif-containing protein 39 (TRIM39) or testis-abundant finger protein, is a 518 amino acid protein belonging to the TRIM/RBCC family that is known to interact with MOAP1. Ubiquitously expressed and existing as two alternatively spliced isoforms, RNF23 is found at highest levels in spleen, testis, brain, kidney, liver, heart and skeletal muscle. RNF23 typically localizes to cytosol but shifts to mitochondria upon co-localization with MOAP1, a short-lived, pro-apoptotic protein which RNF23 prevents from becoming poly-ubiquitinated and degraded, thereby facilitating apoptosis. RNF23 contains one B box-type zinc finger, a B30.2/SPRY domain and a single RING-type zinc finger.

Gen-ID: 56658