Protein RNF21 Antikörper (AbBy Fluor® 488)

Produktnummer ABIN1401682

Produktdetails anti-Protein RNF21 Antikörper (AbBy Fluor® 488)

Target: Protein RNF21 (Rnf227) (RNF21 (Rnf227))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Protein RNF21 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RNF21

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Protein RNF21

Target: Protein RNF21 (Rnf227) (RNF21 (Rnf227))

Andere Bezeichnung: RNF21 (Rnf227 Produkte)

Synonyme: 2310043C11Rik antikoerper, AA589459 antikoerper, AB041807 antikoerper, RNF21 antikoerper, chromodomain helicase DNA binding protein 3, opposite strand antikoerper, Chd3os antikoerper

Hintergrund:

Synonyms: P1, Interferon Responsive Finger Protein 1, Ring Finger Protein 21, Ring finger protein 21 interferon responsive, RNF21, TRIM 34, TRIM34, Tripartite mot containing protein 34, TRI34_HUMAN.

Background: Tripartite motif-containing protein 34 (TRIM34), also known as RING finger protein 21 (RNF21) or interferon-responsive finger protein 1 (IFP1), is a 488 amino acid member of the TRIM family, also known as the RING-B-box coiled-coil (RBCC) family. Members of the RBCC family have an N-terminal RING finger, followed by one or two zinc-binding domains (B-box domains), a leucine coiled-coil region and a variable C-terminal domain. Three isoforms of TRIM34 exist as a result of alternative splicing events. Isoform 1, the most abundant isoform, is highly expressed in placenta, spleen, colon and peripheral blood leukocytes. Studies have shown that Interferon (IFN) stimulation leads to an upregulation of TRIM34. These findings suggest that TRIM34 maybe a downstream effector that mediates IFN activities.

Gen-ID: 53840