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PSMA7 Antikörper (AbBy Fluor® 555)

PSMA7 Reaktivität: Human, Maus, Ratte WB, IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 555
Produktnummer ABIN1402253
  • Target Alle PSMA7 Antikörper anzeigen
    PSMA7 (Proteasome Subunit alpha 7 (PSMA7))
    Reaktivität
    • 52
    • 32
    • 17
    • 1
    Human, Maus, Ratte
    Wirt
    • 44
    • 8
    Kaninchen
    Klonalität
    • 45
    • 7
    Polyklonal
    Konjugat
    • 24
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PSMA7 Antikörper ist konjugiert mit AbBy Fluor® 555
    Applikation
    • 43
    • 17
    • 15
    • 12
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Proteasome 20S alpha 7
    Isotyp
    IgG
    Top Product
    Discover our top product PSMA7 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    PSMA7 (Proteasome Subunit alpha 7 (PSMA7))
    Abstract
    PSMA7 Produkte
    Synonyme
    C6 antikoerper, HSPC antikoerper, RC6-1 antikoerper, XAPC7 antikoerper, C6-I antikoerper, DDBDRAFT_0185059 antikoerper, DDBDRAFT_0217080 antikoerper, DDB_0185059 antikoerper, DDB_0217080 antikoerper, hspc antikoerper, rc6-1 antikoerper, xapc7 antikoerper, psma7 antikoerper, psma4-B antikoerper, proteasome subunit alpha 7 antikoerper, proteasome (prosome, macropain) subunit, alpha type 7 antikoerper, 20S proteasome subunit alpha-7 antikoerper, proteasome subunit alpha 7 S homeolog antikoerper, proteasome subunit alpha 7 L homeolog antikoerper, PSMA7 antikoerper, Psma7 antikoerper, psmA7 antikoerper, psma7 antikoerper, psma7.S antikoerper, psma7.L antikoerper
    Hintergrund

    Synonyms: C6 antibody HSPC, Proteasome prosome macropain subunit alpha type 7, Proteasome alpha 7 subunit, Proteasome subunit alpha 4, Proteasome subunit alpha type 7, Proteasome subunit alpha type-7, Proteasome subunit RC6 1, Proteasome subunit RC6-1, Proteasome subunit XAPC7, PSA7_HUMAN, PSMA7, RC6 1, XAPC7.

    Background: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH . The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response.

    Gen-ID
    5688
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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