MID1 Antikörper (AA 200-250) (Biotin)
-
- Target Alle MID1 Antikörper anzeigen
- MID1 (Midline 1 (MID1))
-
Bindungsspezifität
- AA 200-250
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser MID1 Antikörper ist konjugiert mit Biotin
-
Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Midline-1/RNF59
- Isotyp
- IgG
- Top Product
- Discover our top product MID1 Primärantikörper
-
-
- Applikationshinweise
-
WB 1:300-5000
IHC-P 1:200-400 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
-
- Target
- MID1 (Midline 1 (MID1))
- Andere Bezeichnung
- Midline-1 (MID1 Produkte)
- Synonyme
- BBBG1 antikoerper, FXY antikoerper, GBBB1 antikoerper, MIDIN antikoerper, OGS1 antikoerper, OS antikoerper, OSX antikoerper, RNF59 antikoerper, TRIM18 antikoerper, XPRF antikoerper, ZNFXY antikoerper, 61B3-R antikoerper, DXHXS1141 antikoerper, Fxy antikoerper, Trim18 antikoerper, Midline1 antikoerper, bbbg1 antikoerper, fxy antikoerper, gbbb1 antikoerper, midin antikoerper, ogs1 antikoerper, osx antikoerper, rnf59 antikoerper, trim18 antikoerper, xprf antikoerper, znfxy antikoerper, midline 1 antikoerper, midline 1 L homeolog antikoerper, MID1 antikoerper, Mid1 antikoerper, mid1 antikoerper, mid1.L antikoerper
- Hintergrund
-
Synonyms: BBBG1, Finger on X and Y mouse homolog of antibody, FXY, GBBB1, MID-1, Mid1, Midin, Midline 1 Opitz/BBB syndrome, Midline 1, Midline 1 ring finger, Midline 1 RING finger protein, Midline-1, Midline1, OGS1, OSX, Putative transcription factor XPRF, RING finger protein 59, RNF59, TRI18, TRI18_HUMAN, TRIM18, Tripartite mot containing protein 18, Tripartite mot protein TRIM18, Tripartite mot-containing protein 18, XPRF, Zinc finger X and Y antibody, ZNFXY.
Background: Midline-1 (Tripartite motif-containing protein 18, Putative transcription factor XPRF, RING finger protein 59) is a 667 amino acid protein encoded by the human gene MID1. Midline-1 belongs to the TRIM/RBCC family and contains two B box-type zinc fingers, one B30.2/SPRY domain, one COS domain, one fibronectin type-III domain and one RING-type zinc finger. Midline-1 is believed to have E3 ubiquitin ligase activity which targets the catalytic subunit of protein phosphatase 2 for degradation. It is a cytoplasmic protein found as a homodimer or heterodimer with Midline-2. It also interacts with IGBP1 (Lymphocyte signaling protein A4). Defects in MID1 are the cause of Opitz syndrome type I (OS-I). OS-I is an X-linked recessive disorder characterized by hypertelorism, genital-urinary defects such as hypospadias in males and splayed labia in females, lip-palate-laryngotracheal clefts, imperforate anus, developmental delay and congenital heart defects. OS-I mutations produce proteins with a decreased affinity for microtubules.
- Gen-ID
- 4281
- UniProt
- O15344
-