CHAF1A Antikörper (Biotin)

Produktnummer ABIN1402447

Produktdetails anti-CHAF1A Antikörper (Biotin)

Target: CHAF1A (Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHAF1A Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human p150 CAF1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu CHAF1A

Target: CHAF1A (Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A))

Andere Bezeichnung: p150 CAF1 (CHAF1A Produkte)

Synonyme: CHAF1A antikoerper, CAF-1 antikoerper, CAF1 antikoerper, CAF1B antikoerper, CAF1P150 antikoerper, P150 antikoerper, AL023013 antikoerper, AL024058 antikoerper, Cac1p antikoerper, CAF-1P150 antikoerper, CAF-I-p150 antikoerper, CAF-Ip150 antikoerper, caip150 antikoerper, wu:fd14g10 antikoerper, zgc:153930 antikoerper, chaf1a-b antikoerper, xp150 antikoerper, chromatin assembly factor 1 subunit A antikoerper, chromatin assembly factor 1, subunit A (p150) antikoerper, chromatin assembly factor 1 subunit A S homeolog antikoerper, Chaf1a antikoerper, CHAF1A antikoerper, LOC100447657 antikoerper, chaf1a antikoerper, chaf1a.S antikoerper

Hintergrund:

Synonyms: CAF-1 p150, CAF 1 150 kDa subunit, CAF 1, CAF 1 subunit A, CAF, CAF I 150 kDa subunit, CAF I p150, CAF Ip150, CAF-1 subunit A, CAF-I 150 kDa subunit, CAF-I p150, CAF1 150 kDa subunit, CAF1, CAF1 p150 Subunit, CAF1 subunit A, CAF1A, CAF1A, CAF1A_HUMAN, CAF1B, CAF1P150, CAF1P155, CAF1P155, CHAF1A, Chromatin assembly factor 1 subunit A, Chromatin Assembly Factor 1 Subunit A p150, Chromatin assembly factor I 150 kDa, Chromatin assembly factor I 150 kDa, Chromatin Assembly Factor I, Chromatin assembly factor I p150 subunit, DCAF1, hp150, Nucleosome Remodeling Factor 150 kDa Subunit, NURF150, P150.

Background: Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA, histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci (By similarity). The CCR4-NOT complex functions as general transcription regulation complex. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.

Gen-ID: 10036