PYGB Antikörper (AbBy Fluor® 488)
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- Target Alle PYGB (GPBB) Antikörper anzeigen
- PYGB (GPBB) (phosphorylase, Glycogen, Brain (GPBB))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PYGB Antikörper ist konjugiert mit AbBy Fluor® 488
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Applikation
- Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human GPBB/PYGB
- Isotyp
- IgG
- Top Product
- Discover our top product GPBB Primärantikörper
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- Applikationshinweise
- IF(IHC-P) 1:50-200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- PYGB (GPBB) (phosphorylase, Glycogen, Brain (GPBB))
- Andere Bezeichnung
- GPBB (GPBB Produkte)
- Synonyme
- GPBB antikoerper, GLYPHOA antikoerper, glycogen phosphorylase B antikoerper, phosphorylase, glycogen; brain antikoerper, brain glycogen phosphorylase antikoerper, phosphorylase, glycogen; brain S homeolog antikoerper, PYGB antikoerper, pygb antikoerper, Pygb antikoerper, pygb.S antikoerper
- Hintergrund
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Synonyms: Brain glycogen phosphorylase, Glycogen phosphorylase B, Glycogen phosphorylase brain form, Glycogen Phosphorylase Isoenzyme BB, Glycogen phosphorylase, brain form, MGC9213, Phosphorylase glycogen brain, PYGB, PYGB_HUMAN.
Background: Glycolysis is an evolutionarily conserved series of ten chemical reactions that utilizes eleven enzymes to concomitantly generate pyruvate and ATP from glucose. fructose kinase-2/fructose 2,6-bisphosphatase (PFK-2) stimulates the synthesis and degradation of fructose 2,6-bisphosphate. Glycogen phosphorylase (also known as GP) is an allosteric enzyme important in carbohydrate metabolism. Its activity is regulated through either noncovalent binding of metabolites or by covalent modification. Glycogen phosphorylase catalyzes the phosphorylation of glycogen to Glc-1-P. There are three genes which encode the brain, liver and muscle forms of glycogen phosphorylase, PYGB, PYGL and PYGM. Because of its fundamental role in the metabolism of glycogen, glycogen phosphorylase has been a target for the design of inhibitory compounds, which could be valuable in the therapeutic treatment of type 2 diabetes mellitus.
- Gen-ID
- 5834
- Pathways
- Cellular Glucan Metabolic Process
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