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INIP Antikörper (AA 1-50) (Biotin)

INIP Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1403029
  • Target Alle INIP Antikörper anzeigen
    INIP (INTS3 and NABP Interacting Protein (INIP))
    Bindungsspezifität
    AA 1-50
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 15
    Kaninchen
    Klonalität
    • 15
    Polyklonal
    Konjugat
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser INIP Antikörper ist konjugiert mit Biotin
    Applikation
    • 14
    • 13
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SOSSC/C9orf80
    Isotyp
    IgG
    Top Product
    Discover our top product INIP Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    INIP (INTS3 and NABP Interacting Protein (INIP))
    Andere Bezeichnung
    SOSSC (INIP Produkte)
    Synonyme
    C8H9orf80 antikoerper, C9orf80 antikoerper, SSBIP1 antikoerper, INIP antikoerper, HSPC043 antikoerper, MISE antikoerper, SOSSC antikoerper, hSSBIP1 antikoerper, 1110054O05Rik antikoerper, 2610312O17Rik antikoerper, AA399876 antikoerper, Ssbip1 antikoerper, SOSS-C antikoerper, ssbip1 antikoerper, zgc:56259 antikoerper, zgc:86662 antikoerper, c9orf80 antikoerper, hspc043-a antikoerper, mise antikoerper, sossc antikoerper, ci080 antikoerper, INTS3 and NABP interacting protein antikoerper, ints3 and nabp interacting protein antikoerper, INTS3 and NABP interacting protein S homeolog antikoerper, INIP antikoerper, Inip antikoerper, inip antikoerper, inip.S antikoerper
    Hintergrund

    Synonyms: INIP, Chromosome 9 open reading frame 80, hSSBIP1, MISE, RP11-276E15.2, Sensor of single-strand DNA complex subunit C, Sensor of ssDNA subunit C, Single-stranded DNA-binding protein-interacting protein 1, SOSS C, SOSS complex subunit C, SOSS-C, SOSSC, SOSSC_HUMAN, SSB-interacting protein 1, Ssbip1, C9orf80, INTS3- and NABP-interacting protein

    Background: The SOSS (Sensor of single-strand DNA) complex consists of multiple proteins that promote DNA repair and G2/M checkpoint downstream of the MRN (Mre11, Rad50 and Nbs1) complex. The complex is composed of SSBP1, INTS3 and C9orf80. Specifically, the SOSS complex binds to ssDNA at DNA lesions that influences diverse endpoints in the cellular DNA damage response. The complex is required for efficient homologous recombination-dependent repair of double-stranded breaks and ATM-dependent signaling pathways. C9orf80, also known as SOSS complex subunit C and Single-stranded DNA-binding protein-interacting protein 1 (SSBIP1), is a 104 amino acid nuclear protein that is a component of the SOSS complex. Upon DNA damage, C9orf80 along with other components of the SOSS complex migrate to the nucleus. There are two isoforms of C9orf80 that are produced as a result of alternative splicing events.

    Gen-ID
    58493
    UniProt
    Q9NRY2
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