BPGM Antikörper (Biotin)

Produktnummer ABIN1403197

Produktdetails anti-BPGM Antikörper (Biotin)

Target: BPGM (2,3-bisphosphoglycerate Mutase (BPGM))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BPGM Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BPGM

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu BPGM

Target: BPGM (2,3-bisphosphoglycerate Mutase (BPGM))

Andere Bezeichnung: BPGM (BPGM Produkte)

Synonyme: DPGM antikoerper, AI323730 antikoerper, AL022789 antikoerper, C86192 antikoerper, Ab2-098 antikoerper, zgc:92230 antikoerper, Bisphosphoglycerate mutase antikoerper, bisphosphoglycerate mutase antikoerper, 2,3-bisphosphoglycerate mutase antikoerper, bisphosphoglycerate mutase S homeolog antikoerper, pmge antikoerper, BPGM antikoerper, Bpgm antikoerper, bpgm antikoerper, bpgm.S antikoerper

Hintergrund:

Synonyms: 2,3-bisphosphoglycerate mutase, 2,3-bisphosphoglycerate synthase, 3-bisphosphoglycerate mutase, 3-bisphosphoglycerate synthase, 3-diphosphoglycerate mutase, Ab2 098, AI323730, AL022789, Bisphosphoglycerate mutase, BPG dependent PGAM, BPG-dependent PGAM , Bpgm, BPGM, C86192, DPGM, Erythrocyte 2,3 bisphosphoglycerate mutase, PMGE_HUMAN, 2,3-bisphosphoglycerate mutase, erythrocyte, erythrocyte, 2 antibody.

Background: BPGM (2,3-bisphosphoglycerate mutase) is a 259 amino acid protein that belongs to the phosphoglycerate mutase family and exists as a homodimer that plays a crucial role in the regulation of hemoglobin oxygen. Specifically, BPGM catalyzes the conversion of 3-D-glyceroyl phosphate to 2,3-bisD-glycerate (2,3-BPG), a reaction that is essential for controlling the concentration of 2,3-BPG within the cell. The gene encoding BPGM maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5 % of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. Involvement in disease:Defects in BPGM are the cause of bisphosphoglycerate mutase deficiency (BPGMD) . A disease characterized by hemolytic anemia, splenomegaly, cholelithiasis and cholecystitis.

Gen-ID: 669