FECH Antikörper (Biotin)

Produktnummer ABIN1403209

Produktdetails anti-FECH Antikörper (Biotin)

Target: FECH (Ferrochelatase (FECH))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FECH Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EPB41

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu FECH

Target: FECH (Ferrochelatase (FECH))

Andere Bezeichnung: FECH (FECH Produkte)

Synonyme: AI894116 antikoerper, Fcl antikoerper, fch antikoerper, zgc:109851 antikoerper, EPP antikoerper, FCE antikoerper, CG2098 antikoerper, Dmel\\CG2098 antikoerper, GB15952 antikoerper, ferrochelatase L homeolog antikoerper, ferrochelatase antikoerper, Ferrochelatase antikoerper, ferrochelatase, mitochondrial antikoerper, ferrochelatase HemH antikoerper, ferrochelatase (predicted) antikoerper, fech.L antikoerper, hemH antikoerper, Fech antikoerper, FECH antikoerper, fech antikoerper, FeCH antikoerper, LOC409922 antikoerper, hem15 antikoerper, APH_RS01140 antikoerper

Hintergrund:

Synonyms: EPP, FCE, Ferrochelatase protoporphyria, Ferrochelatase, Ferrochelatase mitochondrial, Heme synthetase, Protoheme ferro lyase, HEMH_HUMAN.

Background: Ferrochelatase catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway, and is localised in the mitochondrion. Defects in ferrochelatase are associated with protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. Porphyrias are a group of inherited or acquired disorders of certain enzymes in the heme biosynthetic pathway (also called porphyrin pathway). They are broadly classified as hepatic porphyrias or erythropoietic porphyrias, based on the site of the overproduction and mainly accumulation of the porphyrins (or their chemical precursors). They manifest with either skin problems, or neurological complications, or occasionally both.

Gen-ID: 2235

Pathways: Transition Metal Ion Homeostasis