PIGA Antikörper (Biotin)
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- Target Alle PIGA Antikörper anzeigen
- PIGA (Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PIGA Antikörper ist konjugiert mit Biotin
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human PIGA
- Isotyp
- IgG
- Top Product
- Discover our top product PIGA Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- PIGA (Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA))
- Andere Bezeichnung
- PIGA (PIGA Produkte)
- Hintergrund
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Synonyms: GlcNAc PI synthesis protein, GlcNAc-PI synthesis protein, GPI3, Phosphatidylinositol glycan anchor biosynthesis class A, phosphatidylinositol glycan anchor biosynthesis, class A paroxysmal nocturnal hemoglobinuria, Phosphatidylinositol N-acetylglucosaminyltransferase subunit A, PIG A, PIG-A, PIGA_HUMAN, Phosphatidylinositol-glycan biosynthesis class A protein, PIG-A.
Background: PIGA belongs to the glycosyltransferase 1 family and is necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, the very early intermediate in GPI-anchor biosynthesis. Defects in PIGA are the cause of paroxysmal nocturnal hemoglobinuria (PNH) which is an acquired hemolytic blood disorder characterized by chronic hemolysis with hemoglobinuria, increased tendency to venous thrombosis, and variable degrees of bone marrow failure.
- Gen-ID
- 5277
- Pathways
- Inositol Metabolic Process
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