FNTA Antikörper (AbBy Fluor® 488)
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- Target Alle FNTA Antikörper anzeigen
- FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FNTA Antikörper ist konjugiert mit AbBy Fluor® 488
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Applikation
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human PGGT1A/FNTA
- Isotyp
- IgG
- Top Product
- Discover our top product FNTA Primärantikörper
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- Applikationshinweise
- IF(IHC-P) 1:50-200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))
- Andere Bezeichnung
- PGGT1A (FNTA Produkte)
- Synonyme
- ATFTA antikoerper, FARNESYLTRANSFERASE A antikoerper, FARNESYLTRANSFERASE SUBUNIT A antikoerper, PFT/PGGT-IALPHA antikoerper, PLP antikoerper, PLURIPETALA antikoerper, farnesyltransferase A antikoerper, FPTA antikoerper, PGGT1A antikoerper, PTAR2 antikoerper, PFAS antikoerper, FTA antikoerper, farnesyltransferase A antikoerper, farnesyltransferase, CAAX box, alpha antikoerper, FTA antikoerper, FNTA antikoerper, Fnta antikoerper
- Hintergrund
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Synonyms: CAAX farnesyltransferase alpha subunit, Farnesyl protein transferase alpha subunit, Farnesyltransferase CAAX box alpha, Farnesyltransferase, CAAX box, alpha, FPTA, FTase alpha, GGTase I alpha, PGGT1A, Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit, Protein prenyltransferase alpha subunit repeat containing 2, PTAR2, Ras proteins prenyltransferase alpha, Ras proteins prenyltransferase subunit alpha, Type I protein geranyl geranyltransferase alpha subunit, FNTA_HUMAN.
Background: FNTA, also known as CAAX farnesyltransferase (FTase), attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the so-called CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine. This type of posttranslational modification provides a mechanism for membrane localization of proteins that lack a transmembrane domain. This enzyme has the remarkable property of farnesylating peptides as short as four residues in length that conform to the CAAX consensus sequence. FNTA is also a specific cytoplasmic interactor of the transforming growth factor-beta and activin type I receptors. It is likely to be a key component of the signaling pathway which involves p21ras, an important substrate for farnesyltransferase.
- Gen-ID
- 2339
- Pathways
- Response to Water Deprivation, Regulation of G-Protein Coupled Receptor Protein Signaling
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