GID8/C20orf11 Antikörper (AbBy Fluor® 488)

Produktnummer ABIN1404100

Produktdetails anti-GID8/C20orf11 Antikörper (AbBy Fluor® 488)

Target: GID8/C20orf11 (GID8) (GID Complex Subunit 8 Homolog (GID8))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GID8/C20orf11 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TWA1/C20orf11

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GID8/C20orf11

Target: GID8/C20orf11 (GID8) (GID Complex Subunit 8 Homolog (GID8))

Andere Bezeichnung: C20orf11 (GID8 Produkte)

Synonyme: C20orf11 antikoerper, TWA1 antikoerper, Bwk1 antikoerper, 2310003C23Rik antikoerper, C13H20orf11 antikoerper, GID complex subunit 8 homolog antikoerper, GID complex subunit 8 antikoerper, GID8 antikoerper, Gid8 antikoerper

Hintergrund:

Synonyms: Chromosome 20 open reading frame 11, CT011_HUMAN, Protein C20orf11, Twa1, Two hybrid associated protein 1, Two hybrid-associated protein 1 with Ran BP-M, Two hybrid associated protein 1 with RanBPM, Two hybrid-associated protein 1 with RanBPM.

Background: TWA1 is a 228 amino acid nuclear protein that is highly conserved throughout evolution. TWA1 interacts with Ran BP-M, a protein that is implicated in a diverse array of cellular processes including DNA replication, entry into and exit from mitosis, and the transport of RNA and proteins through the nuclear pore complex. Together, Ran BP-M and TWA1 form a complex with cytoplasmic Muskelin, a mediator of cell spreading. It is thought that this complex plays a role in the Ran GTPase cycle and therefore a potential role in the cell cycle. TWA1 contains a LisH-CTLH motif which is usually found in proteins that are involved in nucleokinesis, chromosome segregation, cell migration and microtubule dynamics. The gene encoding TWA1 maps to human chromosome 20, which comprises approximately 2 % of the human genome and contains nearly 63 million bases that encode over 600 genes.