UFD1L Antikörper (AbBy Fluor® 555)

Produktnummer ABIN1404347

Produktdetails anti-UFD1L Antikörper (AbBy Fluor® 555)

Target: UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UFD1L Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human UFD1L

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu UFD1L

Target: UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))

Andere Bezeichnung: UFD1L (UFD1L Produkte)

Synonyme: UFD1 antikoerper, Ufd1 antikoerper, ufd1 antikoerper, wu:fc55f04 antikoerper, zgc:92341 antikoerper, Ufd1l antikoerper, ubiquitin recognition factor in ER associated degradation 1 antikoerper, ubiquitin recognition factor in ER-associated degradation 1 antikoerper, ubiquitin fusion degradation 1 like (yeast) antikoerper, ubiquitin recognition factor in ER associated degradation 1 S homeolog antikoerper, ubiquitin fusion degradation protein 1 homolog antikoerper, Ubiquitin Fusion Degradation (yeast UFD homolog) antikoerper, UFD1 antikoerper, Ufd1 antikoerper, UFD1L antikoerper, ufd1.S antikoerper, ufd1l antikoerper, ufd1 antikoerper, EHI_125920 antikoerper, LOC100166745 antikoerper, LOC100635687 antikoerper, LOC100648660 antikoerper, ufd-1 antikoerper

Hintergrund:

Synonyms: UB fusion protein 1, Ubiquitin fusion degradation 1 like yeast, Ubiquitin fusion degradation 1 like, Ubiquitin fusion degradation protein 1 homolog, UFD1, UFD1L.

Background: UFD1L is a member of the UFD1 family of proteins and is a component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. This complex, also containing UFD1L, VCP and NPLOC4, binds ubiquitinated proteins and is required for the export of misfolded proteins from the ER to the cytoplasm for disposal. The NPLOC4-UFD1L-VCP complex also regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. UFD1L gene hemizygosity is the cause of some developmental defects including DiGeorge syndrome (DGS), velo-cardio-facial syndrome (VCFS) and Opitz G/BBB syndrome. UFD1L has 2 named isoforms produced by alternative splicing.

Gen-ID: 7353