INTS3 Antikörper (AA 960-998) (AbBy Fluor® 647)
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- Target Alle INTS3 Antikörper anzeigen
- INTS3 (Integrator Complex Subunit 3 (INTS3))
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Bindungsspezifität
- AA 960-998
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser INTS3 Antikörper ist konjugiert mit AbBy Fluor® 647
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Applikation
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human INTS3
- Isotyp
- IgG
- Top Product
- Discover our top product INTS3 Primärantikörper
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- Applikationshinweise
- IF(IHC-P) 1:50-200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- INTS3 (Integrator Complex Subunit 3 (INTS3))
- Andere Bezeichnung
- INTS3 (INTS3 Produkte)
- Synonyme
- INTS3 antikoerper, Ints3 antikoerper, NV18802 antikoerper, ACYPI009450 antikoerper, DL3335W antikoerper, FCAALL.260 antikoerper, embryo defective 2739 antikoerper, C1orf193 antikoerper, C1orf60 antikoerper, INT3 antikoerper, SOSS-A antikoerper, C77668 antikoerper, RGD1304593 antikoerper, si:dkey-27c15.2 antikoerper, integrator complex subunit 3 antikoerper, integrator complex subunit 3 L homeolog antikoerper, embryo defective 2739 antikoerper, INTS3 antikoerper, ints3.L antikoerper, CpipJ_CPIJ008133 antikoerper, ints3 antikoerper, Ints3 antikoerper, LOC100168776 antikoerper, emb2739 antikoerper
- Hintergrund
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Synonyms: INT3, SOSSA, SOSS-A, C1orf60, C1orf193, Integrator complex subunit 3, SOSS complex subunit A, Sensor of single-strand DNA complex subunit A, Sensor of ssDNA subunit A, INTS3
Background: Component of the Integrator complex. The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. The SOSS complex is required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. In the SOSS complex, it is required for the assembly of the complex and for stabilization of the complex at DNA damage sites.
- Gen-ID
- 65123
- UniProt
- Q68E01
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