COA6 Antikörper (Biotin)

Produktnummer ABIN1404655

Produktdetails anti-COA6 Antikörper (Biotin)

Target: COA6 (Cytochrome C Oxidase Assembly Factor 6 Homolog (COA6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COA6 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf31

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu COA6

Target: COA6 (Cytochrome C Oxidase Assembly Factor 6 Homolog (COA6))

Andere Bezeichnung: C1orf31 (COA6 Produkte)

Synonyme: C1orf31 antikoerper, cytochrome c oxidase assembly factor 6 antikoerper, COA6 antikoerper

Hintergrund:

Synonyms: C1orf31, CA031_HUMAN, Chromosome 1 open reading frame 31, Hypothetical protein LOC388753, RP5-827C21.3, Uncharacterized protein C1orf31.

Background: The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. C1orf31 is a 125 amino acid mitochondrial protein that belongs to the cytochrome c oxidase subunit 6B family. There are three isoforms of C1orf31 that are produced as a result of alternative splicing events. The gene encoding C1orf31 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration.

Gen-ID: 388753