AIDA Antikörper (Biotin)

Produktnummer ABIN1404751

Produktdetails anti-AIDA Antikörper (Biotin)

Target: AIDA (Axin Interactor, Dorsalization Associated (AIDA))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AIDA Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf180/AIDA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu AIDA

Target: AIDA (Axin Interactor, Dorsalization Associated (AIDA))

Andere Bezeichnung: C1orf80 (AIDA Produkte)

Synonyme: C1orf80 antikoerper, RP11-378J18.7 antikoerper, 2610208M17Rik antikoerper, BC004835 antikoerper, zgc:73327 antikoerper, AIDA antikoerper, axin interactor, dorsalization associated antikoerper, axin interactor, dorsalization associated L homeolog antikoerper, axin interactor, dorsalization associated S homeolog antikoerper, AIDA antikoerper, Aida antikoerper, aida antikoerper, aida.L antikoerper, aida.S antikoerper

Hintergrund:

Synonyms: dorsalization-associated protein, AIDA, AIDA_HUMAN, Axin interaction partner and dorsalization antagonist, Axin interactor, Axin interactor, dorsalization associated, Chromosome 1 open reading frame 80, UPF0491 protein C1orf80.

Background: AIDA, also known as C1orf80, is a 306 amino acid protein that belongs to the axin interactor family. Expressed in a variety of tissues, including skeletal muscle and heart, AIDA functions as a ventralizing factor during embryogenesis, disrupting Axin homodimerization and inhibiting Axin-mediated JNK activation. Axin, a scaffold protein, is important for both JNK signaling and the canonical Wnt pathway, two processes that play an essential role in embryonic dorsoventral patterning. Disruption of Axin by AIDA results in the negative regulation of JNK and Wnt signaling, thereby affecting embryonic developmental events. Three isoforms of AIDA exist due to alternative splicing events.

Gen-ID: 439927