C2orf40 Antikörper (Biotin)

Produktnummer ABIN1404781

Produktdetails anti-C2orf40 Antikörper (Biotin)

Target: C2orf40 (Chromosome 2 Open Reading Frame 40 (C2orf40))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C2orf40 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ECRG4/C2orf40

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu C2orf40

Target: C2orf40 (Chromosome 2 Open Reading Frame 40 (C2orf40))

Andere Bezeichnung: ECRG4 (C2orf40 Produkte)

Synonyme: ECRG4 antikoerper, ecrg4 antikoerper, ecrg4-A antikoerper, Ecrg4 antikoerper, chromosome 2 open reading frame, human C2orf40 antikoerper, chromosome 13 open reading frame, human C2orf40 antikoerper, chromosome 11 open reading frame, human C2orf40 antikoerper, chromosome 2 open reading frame 40 antikoerper, chromosome 2 open reading frame 40 L homeolog antikoerper, RIKEN cDNA 1500015O10 gene antikoerper, similar to RIKEN cDNA 1500015O10 antikoerper, C2H2orf40 antikoerper, C13H2orf40 antikoerper, C11H2orf40 antikoerper, C2orf40 antikoerper, c2orf40.L antikoerper, 1500015O10Rik antikoerper, RGD1305645 antikoerper

Hintergrund:

Synonyms: AUGN_HUMAN, Augurin, C2orf40, Esophageal cancer-related gene 4 protein.

Background: ECRG4, also known as augurin or C2orf40, is a 148 amino acid secreted protein. Belonging to the augurin family, ECRG4 is thought to be a hormone. It has also been suggested that ECRG4 may act as a tumor suppressor. The gene that encodes ECRG4 maps to human chromosome 2, which consists of 237 million bases encoding over 1,400 genes, making up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes.

Gen-ID: 84417