Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

CPN2 Antikörper (FITC)

CPN2 Reaktivität: Human, Maus, Ratte WB, IF (p) Wirt: Kaninchen Polyclonal FITC
Produktnummer ABIN1405370
  • Target Alle CPN2 Antikörper anzeigen
    CPN2 (Carboxypeptidase N Subunit 2 (CPN2))
    Reaktivität
    • 43
    • 17
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 43
    Kaninchen
    Klonalität
    • 43
    Polyklonal
    Konjugat
    • 14
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CPN2 Antikörper ist konjugiert mit FITC
    Applikation
    • 37
    • 15
    • 15
    • 12
    • 6
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CPN2
    Isotyp
    IgG
    Top Product
    Discover our top product CPN2 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CPN2 (Carboxypeptidase N Subunit 2 (CPN2))
    Andere Bezeichnung
    CPN2 (CPN2 Produkte)
    Synonyme
    cpn2 antikoerper, im:7138819 antikoerper, Cpn2 antikoerper, GB13055 antikoerper, DKFZp470I1612 antikoerper, ACBP antikoerper, 1300018K11Rik antikoerper, RGD1305170 antikoerper, carboxypeptidase N subunit 2 antikoerper, zgc:153913 antikoerper, carboxypeptidase N, polypeptide 2 antikoerper, CPN2 antikoerper, zgc:153913 antikoerper, Cpn2 antikoerper, CpipJ_CPIJ008561 antikoerper, CpipJ_CPIJ010495 antikoerper, CpipJ_CPIJ013628 antikoerper
    Hintergrund

    Synonyms: CPN 2, CPN2, CPN-2, ACBP, Carboxypeptidase N 83 kDa chain, Carboxypeptidase N large subunit, Carboxypeptidase N regulatory subunit, Carboxypeptidase N subunit 2 [Precursor], carboxypeptidase N, polypeptide 2, CPN2_HUMAN.

    Background: CPN2 is a zinc metalloprotease, and cleaves carboxy-terminal arginines and lysines from peptides found in the bloodstream such as complement anaphylatoxins, kinins, and creatine kinase MM (CK-MM). By removing only one amino acid, CPN has the ability to change peptide activity and receptor binding. It is a 280 kDa tetrameric glycoprotein that is synthesized by the liver and secreted into the plasma. It consists of 2 identical 83 kDa regulatory subunits (CPN2) and 2 identical 50 kDa catalytic subunits (CPN1). CPN2, the 83 kDa subunit, binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation. Under some circumstances it may be an allosteric modifier of the catalytic subunit. CPN is a member of a larger family of carboxypeptidases, many of which also cleave arginine and lysine. Because of the highly conserved active sites and the possible redundant functions of carboxypeptidases, it has been difficult to elucidate the role of CPN in disease processes.

    Gen-ID
    1370
Sie sind hier:
Kundenservice