SLURP1 Antikörper (Biotin)

Produktnummer ABIN1405435

Produktdetails anti-SLURP1 Antikörper (Biotin)

Target: SLURP1 (Secreted LY6/PLAUR Domain Containing 1 (SLURP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLURP1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SLURP1/ANUP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu SLURP1

Target: SLURP1 (Secreted LY6/PLAUR Domain Containing 1 (SLURP1))

Andere Bezeichnung: ANUP (SLURP1 Produkte)

Synonyme: RGD1308768 antikoerper, SLURP1 antikoerper, ANUP antikoerper, ARS antikoerper, ArsB antikoerper, LY6LS antikoerper, MDM antikoerper, 1110021N19Rik antikoerper, AI415082 antikoerper, Slurp-1 antikoerper, secreted Ly6/Plaur domain containing 1 antikoerper, secreted LY6/PLAUR domain containing 1 antikoerper, Slurp1 antikoerper, SLURP1 antikoerper

Hintergrund:

Synonyms: Anti neoplastic urinary protein, ANUP, ARS, ARS component B, ARScomponent B 81/S, ArsB, LY6LS, Lymphocyte antigen 6 like secreted, MDM, Results in cobblestone changes in the skin of the palm, Secreted Ly 6/uPAR related protein 1, Secreted LY6/PLAUR domain containing 1, Secreted Ly6/uPAR related protein 1, SLURP-1, SLURP1, SLUR1_HUMAN.

Background: SLURP1, also known as MDM, ARS, ANUP (anti-neoplastic urinary protein), LY6LS or ArsB (ARS component B), is a 103 amino acid secreted protein that exists as a homodimer possessing antitumor activity. Found in esophagus, stomach, exocervix, gums, urine, sweat, saliva, plasma and tears, SLURP1 is most highly expressed in the acrosyringium of the granular layer of skin, where it helps maintain the structure of the keratinocyte layers of the skin. Also considered a marker for late skin differentiation, SLURP1 contains one UPAR/Ly6 domain and is the cause of an autosomal recessive disorder of the skin known as Mal de Meleda (MDM). MDM Is characterized by nail abnormalities, keratotic skin lesions, transgressive palmoplantar keratoderma (PPK), perioral erythema and may sometimes include hyperhidrosis.

Gen-ID: 57152