CACNA1S Antikörper (AA 951-1001) (AbBy Fluor® 488)
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- Target Alle CACNA1S Antikörper anzeigen
- CACNA1S (Calcium Channel, Voltage-Dependent, L Type, alpha 1S Subunit (CACNA1S))
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Bindungsspezifität
- AA 951-1001
- Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CACNA1S Antikörper ist konjugiert mit AbBy Fluor® 488
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Applikation
- Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CACNA1S
- Isotyp
- IgG
- Top Product
- Discover our top product CACNA1S Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- CACNA1S (Calcium Channel, Voltage-Dependent, L Type, alpha 1S Subunit (CACNA1S))
- Andere Bezeichnung
- CACNA1S (CACNA1S Produkte)
- Synonyme
- CACNA1S antikoerper, cav1.1 antikoerper, ca(v)1.1 antikoerper, CACNL1A3 antikoerper, CCHL1A3 antikoerper, Cav1.1 antikoerper, HOKPP antikoerper, HOKPP1 antikoerper, MHS5 antikoerper, TTPP1 antikoerper, hypoPP antikoerper, AW493108 antikoerper, Cchl1a3 antikoerper, fmd antikoerper, mdg antikoerper, sj antikoerper, caV1.1 antikoerper, calcium voltage-gated channel subunit alpha1 S antikoerper, calcium channel, voltage-dependent, L type, alpha 1S subunit S homeolog antikoerper, calcium channel, voltage-dependent, L type, alpha 1S subunit antikoerper, CACNA1S antikoerper, cacna1s.S antikoerper, Cacna1s antikoerper
- Hintergrund
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Synonyms: Voltage-dependent L-type calcium channel subunit alpha-1S, Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle, Voltage-gated calcium channel subunit alpha Cav1.1, CACNA1S, CACH1, CACN1, CACNL1A3
Background: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1S gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle.
- Gen-ID
- 779
- UniProt
- Q13698
- Pathways
- Skeletal Muscle Fiber Development
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