C11ORF74 Antikörper (AbBy Fluor® 488)

Produktnummer ABIN1405582

Produktdetails anti-C11ORF74 Antikörper (AbBy Fluor® 488)

Target: C11ORF74 (Chromosome 11 Open Reading Frame 74 (C11ORF74))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C11ORF74 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C11orf74

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu C11ORF74

Target: C11ORF74 (Chromosome 11 Open Reading Frame 74 (C11ORF74))

Andere Bezeichnung: C11orf74 (C11ORF74 Produkte)

Synonyme: HEPIS antikoerper, chromosome 11 open reading frame 74 antikoerper, chromosome 5 C11orf74 homolog antikoerper, C11orf74 antikoerper, C5H11orf74 antikoerper, c11orf74 antikoerper

Hintergrund:

Synonyms: Chromosome 11 open reading frame 74, FLJ38678, HEPIS, Hypothetical protein LOC119710, Protein HEPIS, CK074_HUMAN.

Background: C11orf74, also known as FLJ38678, is a 123 amino acid protein that exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4 % of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and _ thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.

Gen-ID: 119710