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DGCR6L Antikörper (Biotin)

DGCR6L Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1405813
  • Target Alle DGCR6L Antikörper anzeigen
    DGCR6L (DiGeorge Syndrome Critical Region Gene 6-Like (DGCR6L))
    Reaktivität
    • 46
    • 17
    • 16
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 45
    • 1
    Kaninchen
    Klonalität
    • 46
    Polyklonal
    Konjugat
    • 13
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DGCR6L Antikörper ist konjugiert mit Biotin
    Applikation
    • 36
    • 18
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human DGCR6L
    Isotyp
    IgG
    Top Product
    Discover our top product DGCR6L Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    DGCR6L (DiGeorge Syndrome Critical Region Gene 6-Like (DGCR6L))
    Andere Bezeichnung
    DGCR6L (DGCR6L Produkte)
    Synonyme
    DGCR6L antikoerper, DiGeorge syndrome critical region gene 6-like antikoerper, DiGeorge syndrome critical region gene 6 like antikoerper, DGCR6L antikoerper
    Hintergrund

    Synonyms: DGC6L_HUMAN, DGCR6L, DiGeorge syndrome critical region 6-like protein, Protein DGCR6L.

    Background: Neural crest cell migration to the third and fourth pharyngeal pouches is a critical step in the structural formation of organs that are affected in DiGeorge syndrome. DGCR6 (DiGeorge syndrome critical region 6) is a nuclear protein that plays a role in neural crest cell migration and is located at the DiGeorge syndrome critical region (DGCR) on chromosome 22. Expressed ubiquitously with highest levels in heart, liver and skeletal muscle, DGCR6 shares high homology with the Drosophila gonadal (gdl) protein and with human Laminin-1, both of which are involved in early tissue development. The gene encoding DGCR6, along with other DGCR genes, is deleted in DiGeorge syndrome, a developmental disorder characterized by improper facial, cardiac and palate formation. Upregulation of DGCR6 is implicated in lung and colon adenocarcinomas, as well as in Burkitt?s lymphoma and lymphocytes transformed by EBV. Due to a duplication of the ancestral DGCR6 locus, there are two functional, highly homologous copies of the DGCR6 gene (designated DGCR6 and DGCR6L) on chromosome 22.

    Gen-ID
    85359
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