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CD235b/GYPB Antikörper (AA 21-91) (Cy7)

GYPB Reaktivität: Human IF (cc), IF (p) Wirt: Kaninchen Polyclonal Cy7
Produktnummer ABIN1406220
  • Target Alle CD235b/GYPB (GYPB) Antikörper anzeigen
    CD235b/GYPB (GYPB) (Glycophorin B (GYPB))
    Bindungsspezifität
    • 14
    • 7
    • 2
    AA 21-91
    Reaktivität
    • 24
    • 1
    Human
    Wirt
    • 24
    Kaninchen
    Klonalität
    • 24
    Polyklonal
    Konjugat
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD235b/GYPB Antikörper ist konjugiert mit Cy7
    Applikation
    • 12
    • 12
    • 9
    • 8
    • 6
    • 4
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Glycophorin B
    Isotyp
    IgG
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  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CD235b/GYPB (GYPB) (Glycophorin B (GYPB))
    Andere Bezeichnung
    GYPB (GYPB Produkte)
    Synonyme
    CD235b antikoerper, GPB antikoerper, GPB.NY antikoerper, GYPHe.NY antikoerper, GpMiIII antikoerper, HGpMiIII antikoerper, HGpMiVI antikoerper, HGpMiX antikoerper, MNS antikoerper, PAS-3 antikoerper, SS antikoerper, glycophorin B (MNS blood group) antikoerper, GYPB antikoerper
    Hintergrund

    Synonyms: SS, GPB, MNS, PAS-3, CD235b, GPB.NY, HGpMiX, GpMiIII, HGpMiVI, GYPHe.NY, HGpMiIII, Glycophorin-B, SS-active sialoglycoprotein, Sialoglycoprotein delta, GYPB

    Background: Glycophorins A, B and C are sialoglycoproteins of the human erythrocyte membrane, which bear the antigenic determinants for the MN, Ss and Gerbich blood groups, respectively. Glycophorins span the membrane once and present their amino-terminal end to the extracellular surface of the human erythrocyte. The genetic array of expressed glycophorin surface antigens on erythrocytes defines the blood group phenotype of the individual. The human Glycophorin A gene maps to chromosome 4q31.21, contains seven exons which are 97 % homologous to Glycophorin B, and encodes a 150 amino acid protein. The human Glycophorin B gene maps to chromosome 4q31.21 and encodes a 91 amino acid protein. The human Glycophorin C gene maps to chromosome 2q14.3 and contains four exons. Glycophorin C transcript can generate two protein isoforms. Isoform 1 includes all 4 exons and encodes the full length 128 amino acid protein. Isoform 2 is missing exon 2 and encodes a 109 amino acid protein, which specifies the Yus subtype of the Gerbich phenotype.

    Gen-ID
    2994
    UniProt
    P06028
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