HOXA6 Antikörper (AA 171-233) (HRP)

Produktnummer ABIN1408310

Produktdetails anti-HOXA6 Antikörper (HRP)

Target: HOXA6 (Homeobox A6 (HOXA6))

Bindungsspezifität: AA 171-233

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOXA6 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HOXA6/HOX1B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu HOXA6

Target: HOXA6 (Homeobox A6 (HOXA6))

Andere Bezeichnung: HOXA6/HOX1B (HOXA6 Produkte)

Synonyme: HOX1 antikoerper, HOX1.2 antikoerper, HOX1B antikoerper, Hox-1.2 antikoerper, homeobox A6 antikoerper, HOXA6 antikoerper, hoxa6 antikoerper, Hoxa6 antikoerper

Hintergrund:

Synonyms: Homeo box 1B, Homeo box A6, Homeobox 1B, Homeobox A6, Homeobox protein Hox A6, Homeobox protein Hox-1B, Homeobox protein Hox-A6 antibody Homeobox protein HoxA6, HOX 1, Hox 1B, HOX1, HOX1.2, Hox1B, HOXA6, HX A6, HXA6, HXA6_HUMAN.

Background: The Hox homeobox genes encode proteins that are transcriptional regulators with an established role in embryonic development. HoxA6 (homeobox A6), also known as HOX1B, is a 233 amino acid protein that localizes to the nucleus. Expressed during embryonic development, HoxA6 functions as a sequence-specific DNA-binding transcription factor that is part of a regulatory mechanism that provides cells with positional identities during development. Via its ability to bind DNA, HoxA6 plays an important role in the regulation of gene expression, as well as morphogenesis and differentiation. The gene encoding HoxA6 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5 % of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.