AACS Antikörper (AA 182-228) (HRP)

Produktnummer ABIN1408844

Produktdetails anti-AACS Antikörper (HRP)

Target: AACS (Acetoacetyl-CoA Synthetase (AACS))

Bindungsspezifität: AA 182-228

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AACS Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AACS

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu AACS

Target: AACS (Acetoacetyl-CoA Synthetase (AACS))

Andere Bezeichnung: AACS/ACSF1 (AACS Produkte)

Synonyme: sur-5 antikoerper, An08g04090 antikoerper, AO090001000376 antikoerper, ACSF1 antikoerper, SUR-5 antikoerper, 2210408B16Rik antikoerper, SUR5 antikoerper, zgc:56105 antikoerper, acetoacetyl-CoA synthetase antikoerper, bll4282 antikoerper, acetoacetyl-coa synthetase antikoerper, acetoacetate--CoA ligase antikoerper, acetoacetate-CoA ligase antikoerper, Acetoacetyl-CoA synthetase antikoerper, AACS antikoerper, LOC590598 antikoerper, aacs antikoerper, bll4282 antikoerper, Pfl01_3080 antikoerper, h16_A2860 antikoerper, Mflv_1473 antikoerper, ANI_1_594074 antikoerper, Pput_2653 antikoerper, VIBHAR_RS20435 antikoerper, AOR_1_648164 antikoerper, CC1G_04522 antikoerper, LACBIDRAFT_230952 antikoerper, PLES_33261 antikoerper, PA1997 antikoerper, OB0504 antikoerper, CBU_0766 antikoerper, acsA2 antikoerper, Sde_0006 antikoerper, Plav_1154 antikoerper, AZC_2243 antikoerper, SGR_RS30655 antikoerper, Aacs antikoerper, sur-5 antikoerper

Hintergrund:

Synonyms: Acetoacetyl-CoA synthetase, ACSF1, Acyl-CoA synthetase family member 1, Protein sur-5 homolog, AACS_HUMAN.

Background: ACSF1 is a 672 amino acid protein belonging to the ATP-dependent AMP-binding enzyme family. Encoded by a gene that maps to human chromosome 12q24.31, ACSF1 is highly expressed in kidney, heart and brain, and shows similar neural expression as HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase). Existing as three alternatively spliced isoforms, ACSF1 participates in ATP binding, ligase activity, acetoacetate-CoA ligase activity and nucleotide binding. The ACSF1 promoter is a known PPAR?target gene, with the nuclear receptor recruited to the ACSF1 promoter by direct interaction with stimulating protein-1 (Sp1). ACSF1 activates acetoacetate and is highly regulated by modulators that affect HMGCR and cholesterol biosynthesis.

Gen-ID: 65985

Pathways: Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis