Semaphorin 6C Antikörper (AA 256-305) (HRP)

Produktnummer ABIN1409432

Produktdetails anti-Semaphorin 6C Antikörper (HRP)

Target: Semaphorin 6C (SEMA6C) (Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6C (SEMA6C))

Bindungsspezifität: AA 256-305

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Semaphorin 6C Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SEMA6C

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Semaphorin 6C

Target: Semaphorin 6C (SEMA6C) (Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6C (SEMA6C))

Andere Bezeichnung: SEMA6C (SEMA6C Produkte)

Synonyme: SEMAY antikoerper, m-SemaY antikoerper, m-SemaY2 antikoerper, Semay antikoerper, mKIAA1869 antikoerper, semaphorin 6C antikoerper, sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C antikoerper, SEMA6C antikoerper, Sema6c antikoerper

Hintergrund:

Synonyms: KIAA1869, m Sema Y, m Sema Y2, sema domain, transmembrane domain TM, and cytoplasmic domain, semaphorin 6C, Sema Y antibody Semaphorin 6C [Precursor], Semaphorin Y, SEMAY, SEM6C_HUMAN.

Background: Semaphorins are a family of cell surface and secreted proteins involved in neural development that are conserved from insects to humans. Members of this family are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular semaphorin? domain of approximately 500 amino acids containing 14-16 cysteines, blocks of conserved sequences and no obvious repeats. The transmembrane semaphorins are characterized by an additional 80 amino acid transmembrane domain and an 80-110 amino acid cytoplasmic domain. SEMA6C, also known as SEMA Y, is a transmembrane protein expressed in fetal brain and adult skeletal muscle. Three isoforms of this semaphorin exist due to alternative splicing: SEMA6C 1, SEMA6C 2 and SEMA6C 3. The extracellular domain of SEMA6C induces growth cone collapse of dorsal root ganglion and plays a role in generation or stability of entorhino-hippocampal synapses.