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APH1B Antikörper (AA 51-150) (Cy7)

Aph1b Reaktivität: Maus WB, IF (p), IF (cc) Wirt: Kaninchen Polyclonal Cy7
Produktnummer ABIN1410360
  • Target Alle APH1B (Aph1b) Antikörper anzeigen
    APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))
    Bindungsspezifität
    • 14
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 51-150
    Reaktivität
    • 19
    • 10
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Maus
    Wirt
    • 24
    Kaninchen
    Klonalität
    • 24
    Polyklonal
    Konjugat
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser APH1B Antikörper ist konjugiert mit Cy7
    Applikation
    • 21
    • 12
    • 12
    • 9
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Dog,Cow,Sheep,Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Aph-1b
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))
    Andere Bezeichnung
    Aph-1b (Aph1b Produkte)
    Synonyme
    APH-1B antikoerper, PRO1328 antikoerper, PSFL antikoerper, TAAV688 antikoerper, APH-1B' antikoerper, 2310057K14Rik antikoerper, Aph1c antikoerper, aph-1 homolog B, gamma-secretase subunit antikoerper, aph-1 homolog B, gamma secretase subunit antikoerper, aph1 homolog B, gamma secretase subunit antikoerper, APH1B antikoerper, Aph1b antikoerper
    Hintergrund

    Synonyms: PSFL, APH-1B, PRO1328, TAAV688, Gamma-secretase subunit APH-1B, Aph-1beta, Presenilin-stabilization factor-like, APH1B, UNQ688/PRO1328

    Background: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. Probably present in a minority of gamma-secretase complexes compared to APH1A.

    Gen-ID
    83464
    UniProt
    Q8WW43
    Pathways
    Notch Signalweg, Neurotrophin Signalübertragung
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