EN1 Antikörper (AA 351-392) (Cy5)
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- Target Alle EN1 Antikörper anzeigen
- EN1 (Engrailed Homeobox 1 (EN1))
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Bindungsspezifität
- AA 351-392
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser EN1 Antikörper ist konjugiert mit Cy5
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Homologie
- Dog,Cow,Sheep,Pig,Horse,Chicken
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human EN1/Engrailed 1
- Isotyp
- IgG
- Top Product
- Discover our top product EN1 Primärantikörper
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- Applikationshinweise
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- EN1 (Engrailed Homeobox 1 (EN1))
- Andere Bezeichnung
- EN1/Engrailed 1 (EN1 Produkte)
- Synonyme
- EN1 antikoerper, En-1 antikoerper, Mo-en.1 antikoerper, ENG-1 antikoerper, en-1 antikoerper, en1 antikoerper, eng1 antikoerper, zgc:100771 antikoerper, en1-A antikoerper, engrailed-1 antikoerper, xen1 antikoerper, Gg-En-1 antikoerper, en-3 antikoerper, engrailed antikoerper, engrailed homeobox 1 antikoerper, engrailed 1 antikoerper, engrailed homeobox 1a antikoerper, engrailed homeobox 1 S homeolog antikoerper, EN1 antikoerper, En1 antikoerper, en1a antikoerper, en1.S antikoerper
- Hintergrund
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Synonyms: En 1, EN1, Engrailed 1, Engrailed, Engrailed homeobox 1, Engrailed homolog 1, HME1_HUMAN, Homeobox protein en-1, Homeobox protein engrailed 1, Homeobox protein engrailed-1, Hu-En-1, Mo-en.1.
Background: The engrailed-1 gene, EN1, a murine homolog of the Drosophila homeobox gene engrailed (EN), is required for midbrain and cerebellum development and dorsal/ventral patterning of the limbs as well as apical ectodermal ridge formation. In Drosophila, the EN gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Human EN-1 and EN-2 are homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. Different mutations in the mouse homo-logs, EN-1 and EN-2, produce different developmental defects that frequently are lethal. EN-1 is highly expressed by essentially all dopaminergic neurons in the substantia nigra and ventral tegmentum. EN-1 and EN-2 regulate expres-sion of a-synuclein, a gene that is genetically linked to Parkinson?s disease.
- Gen-ID
- 2019
- UniProt
- Q05925
- Pathways
- Dopaminergic Neurogenesis
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