BRWD3 Antikörper (AA 1701-1802) (Cy3)

Produktnummer ABIN1411353

Produktdetails anti-BRWD3 Antikörper (Cy3)

Target: BRWD3 (Bromodomain and WD Repeat Domain Containing 3 (BRWD3))

Bindungsspezifität: AA 1701-1802

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRWD3 Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BRWD3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu BRWD3

Target: BRWD3 (Bromodomain and WD Repeat Domain Containing 3 (BRWD3))

Andere Bezeichnung: BRWD3 (BRWD3 Produkte)

Synonyme: CG18670 antikoerper, CG31132 antikoerper, CG6400 antikoerper, Dmel\\CG31132 antikoerper, anon-WO0118547.520 antikoerper, anon-WO0118547.620 antikoerper, dBRWD3 antikoerper, l(3)05842 antikoerper, l(3)s5349 antikoerper, ram antikoerper, BRODL antikoerper, MRX93 antikoerper, Brodl antikoerper, D030064D06Rik antikoerper, Gm596 antikoerper, RGD1559445 antikoerper, bromodomain and WD repeat domain containing 3 antikoerper, CG31132 gene product from transcript CG31132-RA antikoerper, PH-interacting protein antikoerper, BRWD3 antikoerper, LOC412406 antikoerper, Brwd3 antikoerper

Hintergrund:

Synonyms: BRODL, Bromo domain containing protein disrupted in leukemia, Bromodomain and WD repeat domain containing 3, Novel WD repeat domain protein, BRWD3_HUMAN.

Background: Members of the WD repeat protein family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis and gene regulation. BRWD3 (bromodomain and WD repeat-containing protein 3) is a 1,802 amino acid protein expressed in fetal liver and most adult tissues. Existing as five alternatively spliced isoforms, BRWD3 contains two bromo domains, nine WD repeats and is thought to play a role in transcription by modifying chromatin. Mutations in the gene encoding BRWD3 are the cause of mental retardation X-linked type 93 (MRX93), which is also known as mental retardation X-linked with macrocephaly (XLMR). MRX93 is characterized by mild intellectual disability, macrocephaly, a prominent forehead and large cupped ears.