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TTC21B Antikörper (AA 1221-1316) (HRP)

TTC21B Reaktivität: Ratte ELISA, IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN1412870
  • Target Alle TTC21B Antikörper anzeigen
    TTC21B (Tetratricopeptide Repeat Domain 21B (TTC21B))
    Bindungsspezifität
    AA 1221-1316
    Reaktivität
    • 14
    • 1
    • 1
    Ratte
    Wirt
    • 15
    Kaninchen
    Klonalität
    • 15
    Polyklonal
    Konjugat
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TTC21B Antikörper ist konjugiert mit HRP
    Applikation
    • 13
    • 13
    • 3
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Ratte
    Homologie
    Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human TTC21B
    Isotyp
    IgG
    Top Product
    Discover our top product TTC21B Primärantikörper
  • Applikationshinweise
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handhabung
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    TTC21B (Tetratricopeptide Repeat Domain 21B (TTC21B))
    Andere Bezeichnung
    TTC21B (TTC21B Produkte)
    Synonyme
    2410066K11Rik antikoerper, Thm1 antikoerper, aln antikoerper, mKIAA1992 antikoerper, RGD1565122 antikoerper, ATD4 antikoerper, IFT139 antikoerper, JBTS11 antikoerper, NPHP12 antikoerper, THM1 antikoerper, sb:cb947 antikoerper, tetratricopeptide repeat domain 21B antikoerper, Ttc21b antikoerper, TTC21B antikoerper, ttc21b antikoerper
    Hintergrund

    Synonyms: ATD4, JBTS11, Nbla10696, NPHP12, Putative protein product of Nbla10696, Tetratricopeptide repeat protein 21B, THM1, TPR repeat protein 21B, TT21B_HUMAN, Ttc21b.

    Background: The tetratricopeptide repeat (TPR) motif is a degenerate, 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways. At the sequence level, there can be up to 16 tandem TPR repeats, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity. TTC21B (tetratricopeptide repeat domain 21B), also known as THM1, is a 1,316 amino acid protein that contains 19 TPR repeats and belongs to the TTC21 family. Localizing to cytoplasm and cytoskeleton, TTC21B exists as two alternatively spliced isoforms and is thought to negatively regulate Shh signal transduction. TTC21B may also be involved in retrograde intraflagellar transport in cilia, and is encoded by a gene that maps to human chromosome 2q24.3.

    Gen-ID
    79809
    UniProt
    Q7Z4L5
    Pathways
    Hedgehog Signalweg
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