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FBXW4 Antikörper (AA 171-270) (HRP)

FBXW4 Reaktivität: Ratte ELISA, IHC (p) Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN1416682
  • Target Alle FBXW4 Antikörper anzeigen
    FBXW4 (F-Box and WD Repeat Domain Containing 4 (FBXW4))
    Bindungsspezifität
    • 14
    • 14
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 171-270
    Reaktivität
    • 33
    • 11
    • 10
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Ratte
    Wirt
    • 34
    • 2
    Kaninchen
    Klonalität
    • 36
    Polyklonal
    Konjugat
    • 18
    • 5
    • 4
    • 3
    • 3
    • 3
    Dieser FBXW4 Antikörper ist konjugiert mit HRP
    Applikation
    • 28
    • 28
    • 9
    • 3
    • 3
    • 3
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Ratte
    Homologie
    Human,Mouse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SHFM3
    Isotyp
    IgG
    Top Product
    Discover our top product FBXW4 Primärantikörper
  • Applikationshinweise
    IHC-P 1:200-400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handhabung
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    FBXW4 (F-Box and WD Repeat Domain Containing 4 (FBXW4))
    Andere Bezeichnung
    SHFM3 (FBXW4 Produkte)
    Synonyme
    dac antikoerper, hag antikoerper, hagoromo antikoerper, wu:fk63g06 antikoerper, FBXW4 antikoerper, DAC antikoerper, FBW4 antikoerper, FBWD4 antikoerper, SHFM3 antikoerper, SHSF3 antikoerper, Dac antikoerper, Fbw4 antikoerper, dactylin antikoerper, dactylyn antikoerper, F-box and WD repeat domain containing 4 antikoerper, F-box and WD-40 domain protein 4 antikoerper, fbxw4 antikoerper, FBXW4 antikoerper, Fbxw4 antikoerper
    Hintergrund

    Synonyms: DAC, Dactylin, F box and WD 40 domain containing protein 4, F box and WD 40 domain protein 4, F box and WD repeat domain containing 4, F box/WD repeat containing protein 4, F box/WD repeat protein 4, F-box and WD-40 domain-containing protein 4, F-box/WD repeat-containing protein 4, FBW 4, FBW4, FBWD 4, FBWD4, FBXW 4, FBXW4, FBXW4_HUMAN, SHFM 3, SHSF 3, SHSF3, Split hand/foot malformation ectrodactyly type.

    Background: Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling.Involvement in disease:Defects in FBXW4 are a cause of split-hand/foot malformation type 3 (SHFM3) . SHFM3 is an autosomal dominant disorder characterized by hypoplasia/aplasia of the central digits with fusion of the remaining digits.

    Gen-ID
    6468
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