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MMS19 Antikörper (AA 851-950) (Cy3)

MMS19 Reaktivität: Human, Maus WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Cy3
Produktnummer ABIN1417967
  • Target Alle MMS19 Antikörper anzeigen
    MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))
    Bindungsspezifität
    • 14
    • 7
    • 1
    • 1
    • 1
    • 1
    AA 851-950
    Reaktivität
    • 28
    • 17
    • 3
    Human, Maus
    Wirt
    • 24
    • 4
    Kaninchen
    Klonalität
    • 26
    • 2
    Polyklonal
    Konjugat
    • 10
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MMS19 Antikörper ist konjugiert mit Cy3
    Applikation
    • 28
    • 12
    • 12
    • 12
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Dog,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MMS 19
    Isotyp
    IgG
    Top Product
    Discover our top product MMS19 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))
    Andere Bezeichnung
    MMS19 (MMS19 Produkte)
    Synonyme
    MET18 antikoerper, MMS19L antikoerper, hMMS19 antikoerper, 2410001K24Rik antikoerper, 2610042O15Rik antikoerper, AI316855 antikoerper, C79368 antikoerper, C86341 antikoerper, Mms19l antikoerper, mms19 antikoerper, mms19l antikoerper, MMS19 homolog, cytosolic iron-sulfur assembly component antikoerper, MMS19 (MET18 S. cerevisiae) antikoerper, MMS19 homolog, cytosolic iron-sulfur assembly component L homeolog antikoerper, MMS19 antikoerper, Mms19 antikoerper, mms19.L antikoerper
    Hintergrund

    Synonyms: MET18, MMS19L, hMMS19, MMS19 nucleotide excision repair protein homolog, MET18 homolog, MMS19-like protein, MMS19

    Background: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.

    Gen-ID
    64210
    UniProt
    Q96T76
    Pathways
    Nuclear Hormone Receptor Binding
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