ZNRF3 Antikörper (AA 120-165) (Cy3)
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- Target Alle ZNRF3 Antikörper anzeigen
- ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))
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Bindungsspezifität
- AA 120-165
- Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ZNRF3 Antikörper ist konjugiert mit Cy3
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Applikation
- Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ZNRF3
- Isotyp
- IgG
- Top Product
- Discover our top product ZNRF3 Primärantikörper
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- Applikationshinweise
- IF(IHC-P) 1:50-200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))
- Andere Bezeichnung
- ZNRF3 (ZNRF3 Produkte)
- Synonyme
- BK747E2.3 antikoerper, RNF203 antikoerper, AA591877 antikoerper, BC019575 antikoerper, Gm1167 antikoerper, zinc and ring finger 3 antikoerper, Znrf3 antikoerper, ZNRF3 antikoerper
- Hintergrund
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Synonyms: RNF203, BK747E2.3, E3 ubiquitin-protein ligase ZNRF3, RING finger protein 203, Zinc/RING finger protein 3, ZNRF3, KIAA1133
Background: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.
- Gen-ID
- 84133
- UniProt
- Q9ULT6
- Pathways
- WNT Signalweg
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